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Record Nr. |
UNINA9910144698903321 |
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Titolo |
Molecular epidemiology of chronic diseases [[electronic resource] /] / editors, Chris Wild, Paolo Vineis, Seymour Garte |
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Pubbl/distr/stampa |
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Chichester, England ; ; Hoboken, NJ, : J. Wiley, 2008 |
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ISBN |
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1-119-96561-6 |
1-282-34292-4 |
9786612342929 |
0-470-72572-9 |
0-470-72571-0 |
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Descrizione fisica |
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1 online resource (386 p.) |
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Altri autori (Persone) |
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WildChris <1959-> |
VineisPaolo |
GarteSeymour J |
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Disciplina |
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Soggetti |
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Molecular epidemiology |
Chronic diseases - Epidemiology |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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MOLECULAR EPIDEMIOLOGY OF CHRONICDISEASES; Contents; Contributors; Acknowledgements; 1 Introduction: why molecular epidemiology?; 2 Study design; 2.1. Introduction: study design at square one; 2.2. Epidemiological measures; 2.3. Bias; 2.4. More on confounding; 2.5. Specifi cities of molecular epidemiology design; 2.6. Conclusions; References; Essential reading; 3 Molecular epidemiological studies that can be nested within cohorts; 3.1. Introduction; 3.2. Case-cohort studies; 3.3. Nested case-control studies |
3.4. Considerations regarding biomarker analyses in case-cohort and nested case-control studies3.5. Conclusion; References; 4 Family studies, haplotypes and gene association studies; 4.1. Introduction; 4.2. Family studies; 4.3. Genetic association studies; 4.4. Discussion; References; 5 Individual susceptibility and gene-environment interaction; 5.1. Individual susceptibility; 5.2. Genetic susceptibility; |
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5.3. Metabolic susceptibility genes; 5.4. Study designs; 5.5. Gene-environment interaction; 5.6. Exposure dose effects in gene-environment interactions |
5.7. Mutational effects of gene-environment interactions5.8. Conclusions; References; 6 Biomarker validation; 6.1. Validity and reliability; 6.2. Biomarker variability; 6.3. Measurement of variation; 6.4. Other issues of validation; 6.5. Measurement error; 6.6. Blood collection for biomarkers; 6.7. Validation of high-throughput techniques; References; 7 Exposure assessment; 7.1. Introduction; 7.2. Initial considerations of an exposure assessment strategy; 7.3. Exposure pathways and routes; 7.4. Exposure dimensions; 7.5. Exposure classifi cation, measurement or modelling |
7.6. Retrospective exposure assessment7.7. Validation studies; 7.8. Quality control issues; References; 8 Carcinogen metabolites as biomarkers; 8.1. Introduction; 8.2. Overview of carcinogen metabolism; 8.3. Examples of carcinogen metabolite biomarkers; 8.4. Summary; References; 9 Biomarkers of exposure: adducts; 9.1. Introduction; 9.2. Methods for adduct detection; 9.3. Adducts identifi ed in human tissue; 9.4. Adducts as biomarkers of occupational and environmental exposure to carcinogens; 9.5. Smoking-related adducts; 9.6. DNA adducts in prospective studies; 9.7. Conclusions; References |
10 Biomarkers of mutation and DNA repair capacity10.1. Introduction; 10.2. Classifi cation of mutations; 10.3. Mutations in molecular epidemiology; 10.4. DNA repair; 10.5. Classes of DNA repair; 10.6. Common assays to measure DNA repair capacity; 10.7. Integration of DNA repair assays into epidemiological studies; 10.8. Genetic markers for DNA repair capacity; References; 11 High-throughput techniques - genotyping and genomics; 11.1. Introduction; 11.2. Background; 11.3. SNP databases; 11.4. Study types; 11.5. Study design; 11.6. Genotyping technologies |
11.7. Sample and study management and QC |
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Sommario/riassunto |
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""I think this is an excellent book-I recommend it to anyone involved in molecular epidemiology... The 26 chapters are written by topic specialists, in an explanatory, east to read style."" -BTS Newsletter, Summer 2009 ""This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiol |
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2. |
Record Nr. |
UNINA9910823904603321 |
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Titolo |
Nezhat's operative gynecologic laparoscopy and hysteroscopy / / edited by Camran Nezhat, Farr Nezhat, Ceana Nezhat [[electronic resource]] |
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Pubbl/distr/stampa |
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Cambridge : , : Cambridge University Press, , 2008 |
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ISBN |
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1-139-63739-8 |
1-107-17805-3 |
1-281-71702-9 |
9786611717025 |
0-511-40926-5 |
0-511-40790-4 |
0-511-40980-X |
0-511-40716-5 |
0-511-54736-6 |
0-511-40869-2 |
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Edizione |
[Third edition.] |
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Descrizione fisica |
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1 online resource (xxi, 633 pages) : digital, PDF file(s) |
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Disciplina |
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Soggetti |
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Generative organs, Female - Endoscopic surgery |
Laparoscopic surgery |
Hysteroscopy |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Cover; Half-title; Title; Copyright; Contents; Contributing Authors; Forewords; Forewords to the Second Edition; Forewords to the First Edition; Preface; 1 HISTORY OF MODERN OPERATIVE LAPAROSCOPY; 2 EQUIPMENT; 3 ANESTHESIA; 4 LAPAROSCOPIC ACCESS; 5 LAPAROSCOPIC SUTURING; 6 INTRAPERITONEAL AND RETROPERITONEAL ANATOMY; 7 FERTILITY; 8 HYSTEROSCOPY; 9 MANAGEMENT OF ADNEXAL MASSES; 10 ENDOMETRIOSIS; 11 LAPAROSCOPIC ADHESIOLYSIS AND ADHESION PREVENTION; 12 LEIOMYOMAS; 13 HYSTERECTOMY; 14 PELVIC FLOOR; 15 LAPAROSCOPIC TREATMENT OF CHRONIC PELVIC PAIN; 16 GYNECOLOGIC MALIGNANCY |
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17 LAPAROSCOPY IN THE PREGNANT PATIENT18 MINIMAL ACCESS PEDIATRIC SURGERY; 19 LAPAROSCOPIC VASCULAR SURGERY IN 2007; 20 COMPLICATIONS IN LAPAROSCOPY; 21 ADDITIONAL PROCEDURES FOR PELVIC SURGEONS; 22 LAPAROSCOPY SIMULATORS FOR TRAINING BASIC SURGICAL SKILLS, TASKS, AND PROCEDURES; 23 ROBOT-ASSISTED LAPAROSCOPY; 24 HYSTEROSCOPY AND ENDOMETRIAL CANCER; 25 OVERVIEW OF COMPLICATIONS; Appendix A: The Informed Consent andMalpractice; Atlas; Index |
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Sommario/riassunto |
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Gynecologic laparoscopy has evolved into a major surgical tool used to treat a multitude of gynecologic indications. Laparoscopy is the most common surgical procedure performed by gynecologists today. This book catalogs the full spectrum of laparoscopic procedures in gynecology, oncology, and infertility treatment. The authors describe different techniques in minimally invasive surgery and review the evidence-based medical literature supporting these techniques. Included are sections on the management of complications during laparoscopy, ranging from vascular injury to bladder or bowel injury. It contains expanded chapters on laparoscopic anatomy, operative hysteroscopy and pelvic floor repair. The editors have pioneered some of the most important laparoscopic procedures used today. Their work has opened up the video laparoscopy field for surgeons worldwide. The contributors have extensive experience in laparoscopy and hysteroscopy, and many of them have established some of the surgical techniques discussed. High-quality color pictures supplement many of the presentations. |
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