Reading and writing the Mediterranean / / essays by Vincenzo Consolo ; edited by Norma Bouchard and Massimo Lollini

• Record Nr.: UNINA9910456364703321
• Autore: Consolo Vincenzo <1933-2012, >
• Pubbl/distr/stampa: Toronto, [Ontario] ; ; Buffalo, [New York] ; ; London, [England] : , : University of Toronto Press, , 2006; ©2006
• ISBN: 1-4426-8473-9
• Descrizione fisica: 1 online resource (325 p.)
• Collana: Toronto Italian Studies
• Disciplina: 909/.09822
• Soggetti: LITERARY CRITICISM / General; Electronic books.; Mediterranean Region Civilization; Sicily (Italy) Civilization
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Frontmatter -- Contents -- Acknowledgments -- Maps -- Introduction: Vincenzo Consolo and His Mediterranean Paradigm / Bouchard, Norma / Lollini, Massimo -- Part One. Odysseus's Journey: War and Exile -- Conversation between Vincenzo Consolo and Mario Nicolao -- Olive and Wild Olive -- The Ruin of Syracuse -- Algiers: Tradition and New Cultures; Those 'Parabolic Dishers' Who Dream of Italy -- But Is This Sarajevo or Assisi? -- The International Parliament of Writers: Journey to Israel/Palestine -- Report of Basilio Archita -- Men in the Sun -- Diary of Two Journeys to America -- Part Two. Sicilian Travels: Land, Cities, and Sea -- People and Land of Sulphur -- For a Bit of Grass on the Edge of the Feudal Estate -- Tuna Fishing -- Views of the Strait of Messina -- The Eruption of Mount Etna -- The Rebirth of the Val di Noto -- Part Three. Mediterranean Crossroads -- Sicily and Arab Culture -- Ibn Jubayr -- Palermo, Most Beautiful and Defeated -- The Bridge over the Channel of Sicily -- Porta Venezia -- Part Four. Writing as Poetic Memory -- A Day Like Any Other -- For a Metric of Memory -- The Languages of the Forest -- The Disappearance of the Fireflies -- The Smile, Twenty Years Later -- Notes on Sources of the Text -- Selected Bibliography of Vincenzo Consolo's Works -- Selected Critical ; Bibliography -- Contributors
• Sommario/riassunto: Vincenzo Consolo is counted by many critics among the most significant voices in contemporary world literature. This volume makes available for the first in English an edited and annotated volume of Consolo's short stories, essays, and other writings pertaining to the diverse cultures and histories of Sicily and the Mediterranean basin.The Mediterranean region holds a particular fascination for Consolo, who seeks through his writing to recover the memory of a Sicilian and Mediterranean history, which he feels is presently being threatened by the forces of late-capitalist Western culture. His writings about the region also voice a commitment to questions of ethics and human rights, which have been brought to the fore by recent tensions dividing this area and forcing a mass exodus of its people. At a time when this part of the world is under threat from unbridled globalization as well as dangerous forms of ethnic and religious fundamentalism, Consolo's words offer an insightful rethinking of regionalism within a global hierarchy of values. They remind us of the necessity of moderation and contingency, and in so doing, attempt to recover a moral and ethical dimension for our collective life.

Standards of mouse model phenotyping [[electronic resource] /] / edited by Martin Hrabede Angelis, Pierre Chambon, and Steve Brown

• Record Nr.: UNINA9910144698703321
• Pubbl/distr/stampa: Weinheim, : Wiley-VCH, c2006
• ISBN: 1-282-30244-2; 9786612302442; 3-527-61194-0; 3-527-60870-2
• Descrizione fisica: 1 online resource (359 p.)
• Altri autori (Persone): Hrabé de AngelisMartin; ChambonPierre; BrownStephen D. M
• Disciplina: 599.353135
• Soggetti: Mice as laboratory animals; Mice - Genetics; Transgenic mice; Phenotype; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Standards of Mouse Model Phenotyping; Foreword; Table of Contents; Preface; 1 Characterizing Hearing in Mice; 1.1 Introduction; 1.2 Behavioral Tests of Hearing; 1.3 Physiological Tests of Hearing; 1.4 Anatomy of the Ear; 1.5 Conclusions; Acknowledgements; 2 Molecular Phenotyping: Gene Expression Profiling; 2.1 Why this Screen? Medical and Biological Relevance; 2.2 Examples: Diseases of Mouse and Man; 2.3 Diagnostic Methods: History and State of the Art; 2.4 Technical Requirements for Screening Protocols (Short): First and Second Line Approaches; 2.5 Logistics (Whom, When, How Many, Why); 2.5.1 Choice of Platform2.5.2 Biological Samples; 2.6 Trouble Shooting; 2.6.1 Preparation of Hybridization Target; 2.6.2 Critical Issues of Chip Hybridization; 2.6.3 Image Processing and Array Design; 2.7 Short-term Outlook; 3 Screening for Bone and Cartilage Phenotypes in Mice; 3.1 Introduction; 3.1.1 The Skeleton; 3.1.2 Skeletal Development in the ; Embryo; 3.1.3 Growth and Maintenance of Bone and Cartilage; 3.1.4 Diseases Involving Cartilage and Bone; 3.1.5 The Mouse as a Model for Skeletal Diseases; 3.2 Screening Protocols; 3.2.1 Morphological Analysis; 3.2.1.1 Protocol; 3.2.2 X-Ray Analysis3.2.2.1 General; 3.2.2.2 Imaging; 3.2.2.3 X-Ray Analysis; 3.2.2.4 Protocol; 3.2.3 DXA-Analysis; 3.2.3.1 General; 3.2.3.2 Advantages; 3.2.3.3 Disadvantages; 3.2.3.4 Small Animal Applications; 3.2.3.5 Precision and Accuracy; 3.2.3.6 Considerations; 3.2.3.7 Protocol; 3.2.4 Biochemical Bone Markers; 3.2.4.1 Clinical Utility of Biochemical Markers of Bone Turnover in Small Animals; 3.2.4.2 Mouse Markers of Bone Turnover/Metabolism and Hormonal Regulation; 3.2.4.3 Variability/Sensitivity/Sample Choice; 3.2.4.4 Which Markers Should be Used During the Screen?; 3.2.5 Advanced Small Animal Imaging Techniques3.2.5.1 pQCT; 3.2.5.2 μCT; 3.2.5.3 μMRI; 3.2.5.4 Whole-mount Skeletal Preparations; 3.2.5.5 Histomorphometry; 3.2.5.6 Miscellaneous; 3.2.5.7 Order of the Tests; 3.3 Conclusion; List of Abbreviations; Appendix; μCT Volumetric Data Processing; MRI Principles; 4 Clinical Chemical Screen; 4.1 Introduction; 4.1.1 Relevance of the Screen; 4.1.2 Biology and Medical Application; 4.1.2.1 Biology of Clinical Chemical Parameters; 4.1.2.2 Medical Application; 4.2 Diseases in Mouse and Humans; 4.2.1 Diagnostic Impact of Clinical Chemistry; 4.2.2 Clinical Chemistry in Selected Disorders4.2.2.1 Hypercholesterolemia; 4.2.2.2 Albuminuria; 4.2.2.3 Acute Myeloid Leukemia (AML); 4.3 Clinical Chemistry as Diagnostic Tool; 4.3.1 History; 4.3.2 State of the Art; 4.4 Technical Requirements and Screening Protocols; 4.4.1 Technical Requirements; 4.4.1.1 Blood Collection; 4.4.1.2 Sample Preparation; 4.4.1.3 Sample Analysis; 4.4.2 Screening Protocols; 4.4.2.1 Primary Screen; 4.4.2.2 Secondary Screen; 4.4.2.3 Tertiary Screen; 4.5 Logistics of the Screen; 4.5.1 General Considerations; 4.5.2 Lessons from ENU Mutants; 4.6 Trouble Shooting; 4.6.1 Factors Interfering In Vivo
• Sommario/riassunto: This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.