Enzymes in organic synthesis / / [editors: Ruth Porter (organizer) and Sarah Clark

• Record Nr.: UNINA9910144664803321
• Pubbl/distr/stampa: London, : Pitman; Newark, N.J., : Distributed in North America by CIBA Pharmaceutical Co. (Medical Education Division), 1985
• ISBN: 1-280-78415-6; 9786613694546; 0-470-72092-1; 0-470-71862-5
• Descrizione fisica: 1 online resource (258 pages) : illustrations
• Collana: Ciba Foundation symposium ; ; 111
• Altri autori (Persone): PorterRuth; ClarkSarah
• Disciplina: 547/.2
• Soggetti: Organic compounds - Synthesis; Enzymes
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: "Symposium on Organic synthesis using enzymes, held at the Ciba Foundation, London, 15-17 May 1984"--Contents page.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Enzymes in organic synthesis; Contents; Chairman's introduction; An illustrative example of a synthetically useful enzyme: horse liver alcohol dehydrogenase; Discussion; Enzymic synthesis of labelled chiral substances; Discussion; Enzyme-controlled reactions giving alkanols of use in the synthesis of biologically active molecules; Discussion; Large-scale purification of enzymes; Discussion; Immobilized enzymes in organic synthesis; Discussion; General discussion I Synthesis of 5,6-dihydroxycyclohexa-l,3-die; Applications of cell-free enzymes in organic synthesis; Discussion; Chiral products from non-pyridine nucleotide-dependent reductases and methods for NAD(P)H regeneration Discussion; Stereochemistry and synthetic applications of products of fermentation of a,p-unsaturated aromatic aldehydes by baker's yeast; Discussion; Extending the applicability of esterases of low enantioselectivity in asymmetric synthesis; Discussion; Microbial transformations of some ; monoterpenoids and sesquiterpenoids; Discussion; General discussion I1 Synthesis of tetrahydrofolate derivatives; Synthesis of optically active propylene oxides; Creation of novel chiral synthons with enzymes: application to enantioselective synthesis of antibiotics Discussion; Kinetics of trypsin catalysis in the industrial conversion of porcine insulin to human insulin; Discussion; Redesigning enzymes by site-directed mutagenesis; Discussion; The design of new enzyme active sites for the catalysis of specific chemical reactions; Discussion; Final general discussion NAD+ degradation by resting cells; Economic aspects; Applications of enzyme methodology; Index of contributors; Subject index