Immunopotentiation

• Record Nr.: UNINA9910144663403321
• Pubbl/distr/stampa: Amsterdam, : Elsevier, 1973
• ISBN: 1-280-78336-2; 9786613693754; 0-470-72001-8; 0-470-71768-8
• Descrizione fisica: 1 online resource (368 pages)
• Collana: Ciba Foundation symposium (new series) ; ; 18
• Disciplina: 574.2/9
• Soggetti: Immunological adjuvants; Tumors - Immunological aspects
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: "Symposium on Immunopotentiation, held at the Ciba Foundation, London, 18th-19th January 1973"--Participants page.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Immunopotentiation; Contents; Introduction; The cellular targets for the action of adjuvants : T-adjuvants and B-adjuvants; Discussion; The relation of lymphocyte trapping to the mode of action of adjuvants; Discussion; Immunopotentiation by mycobacteria in complete Freund-type adjuvant as the failure of normal immunological homeostasis; Discussion; Effects of adjuvants on different cell types and their interactions in immune responses; Discussion; Cellular mechanisms underlying the adjuvant activity of Corynebacterium parvurn: interactions of activated macrophages with T and B lymphocytes; DiscussionChemotaxis of macrophages : the role of a macrophage-specific cytotaxin from anaerobic corynebacteria and its relation to immunopotentiation in vivo; Discussion; The allogeneic effect on the immune system and its potential applications to tumour immunity; Discussion; Mitogens as probes for immunocyte activ- ation : specific and non-specific paralysis of B cell mitogenesis; Discussion; General Discussion I The T cell-deprived mouse; The use of viruses as immunological potentiators; Discussion; Corynebacterium parvum, a potent immunostimu-lant in experimental infections and in malignanciesDiscussion; Orchidectomy as a method of ; immunopotentiation in mice; Discussion; The nature of immunopotentiation by the anti-tumour polysaccharide lentinan and the significance of biogenic amines in its action; Discussion; The effect of Corynebacterium parvum and other reticuloendothelial stimulants on transplanted tumours in mice; Discussion; Attempt at using systemic immunity adjuvants in experimental and human cancer therapy; Discussion; General Discussion II Restoration of immune capability in cancer patientsSites of action of adjuvants; Conclusion; Index of contributors; Subject index