Congenital disorders of erythropoiesis : in memory of the late Fred Stohlman / / editors, Ruth Porter, David W. Fitzsimons

• Record Nr.: UNINA9910144662403321
• Pubbl/distr/stampa: Amsterdam ; ; Oxford : , : Elsevier, , 1976
• ISBN: 1-280-78348-6; 9786613693877; 0-470-72019-0; 0-470-71787-4
• Descrizione fisica: 1 online resource (418 pages) : illustrations
• Collana: CIBA Foundation symposium ; ; 40 (new ser.)
• Altri autori (Persone): PorterRuth; FitzSimonsDavid W; StohlmanFrederick
• Soggetti: Erythrocytes; Blood - Diseases
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: 'Symposium on Congenital Disorders of Erythropoiesis held at the Ciba Foundation, London, 12-14th March, 1975' - Participants.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Congenital Disorders of Erythropoiesis; Contents; Chairman's opening remarks; Cellular kinetics of erythropoiesis; Discussion; Regulation of fetal and adult erythropoiesis; Discussion; Embryonic erythropoiesis: some experimental systems; Discussion; Oxygen dissociation studies of red cells from chicken, mouse and human embryos; Discussion; General discussion I; Diamond-Blackfan anaemia; Discussion; Fanconi anaemia; Fanconi anaemia: cellular abnormalities and clinical predisposition to malignant disease; Discussion of the two preceding papers; Congenital dyserythropoietic anaemia type I : clinical and experimental aspects Discussion; Congenital dyserythropoietic anaemia type I1 (Hempas); Discussion; Congenital dyserythropoietic anaemias : electron microscopy; Discussion; Pathophysiology of the anaemia in thalassaemia; Discussion; The morphology and kinetics of erythropoiesis in homozygous β-thalassaemia; Discussion; The molecular defect in thalassaemia; Discussion; Cytogenetics of Fanconi ; anaemia and related chromosome disorders; Discussion; Fetal haemoglobin synthesis; Discussion; Regulation of globin gene expression; Discussion; General discussion II: Clinical management Conservative management; Androgen therapy in aplastic anaemia in childhood; Chelating agents; Bone marrow transplants; Genetic manipulation; Antenatal diagnosis; Concluding remarks; Index of contributors; Subject index