Brush border membranes [[electronic resource]]

• Record Nr.: UNINA9910144654903321
• Pubbl/distr/stampa: London, : Pitman, c1983
• ISBN: 1-280-78402-4; 9786613694416; 0-470-72076-X; 0-470-71846-3
• Descrizione fisica: 1 online resource (352 p.)
• Collana: Ciba Foundation symposium ; ; v. 95
• Altri autori (Persone): PorterRuth; CollinsGeralyn M
• Disciplina: 611.0181; 611/.0181
• Soggetti: Cell membranes; Cell physiology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Editors: Ruth Porter (Organizer) and Geralyn M. Collins.; Proceedings of Symposium on: Brush border membranes held at the Ciba Foundation, London, 8-10 June 1982.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Brush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; Discussion; Use of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and ; aminopeptidase to non-brush border sites; General functions of the enterocyte; Molecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush border; Conformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeleton; Photo-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject index