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Record Nr. |
UNINA9910144278503321 |
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Titolo |
Modern alkaloids [[electronic resource] ] : structure, isolation, synthesis and biology / / edited by Ernesto Fattorusso and Orazio Taglialatela-Scafati |
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Pubbl/distr/stampa |
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Weinheim, : Wiley-VCH, c2008 |
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ISBN |
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1-281-31181-2 |
9786611311810 |
3-527-62107-5 |
3-527-62108-3 |
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Descrizione fisica |
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1 online resource (691 p.) |
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Altri autori (Persone) |
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FattorussoErnesto |
Taglialatela-ScafatiOrazio |
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Disciplina |
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Soggetti |
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Alkaloids - Structure |
Alkaloids |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Modern Alkaloids; Contents; Preface; List of Contributors; I Bioactive Alkaloids: Structure and Biology; 1 Ecological Roles of Alkaloids; 1.1 Introduction: Defense Strategies in Plants; 1.2 Ecological Roles of Alkaloids; 1.3 Modes of Action; 1.3.1 Unspecific Interactions; 1.3.2 Specific Interactions; 1.3.3 Cytotoxicity of Alkaloids; 1.4 Evolution of Alkaloidal Defense Systems; 1.5 Conclusions; 2 Antitumor Alkaloids in Clinical Use or in Clinical Trials; 2.1 Introduction; 2.2 Antitumor Alkaloids in Clinical Use; 2.2.1 Vinca Alkaloids; 2.2.1.1 Vinblastine (VLB, 1); 2.2.1.2 Vincristine (VCR, 2) |
2.2.1.3 Vindesine (VDS, 3)2.2.1.4 Vinorelbine (VRLB, 4); 2.2.1.5 Vinflunine (VFL, 5); 2.2.2 Camptothecin and Analogs; 2.2.2.1 Camptothecin (CPT, 6); 2.2.2.2 Irinotecan (CPT-11); 2.2.2.3 Topotecan; 2.2.2.4 Exatecan; 2.2.2.5 Gimatecan; 2.2.2.6 Karenitecin; 2.2.2.7 Lurtotecan; 2.2.2.8 Rubitecan (9-nitrocamptothecin); 2.2.3 Taxanes; 2.2.3.1 Paclitaxel; 2.2.3.2 Docetaxel; 2.3 Antitumor Alkaloids in Clinical Trials; 2.3.1 Ecteinascidin-743 (Yondelis, Trabectedin); 2.3.2 7-Hydroxystaurosporine (UCN-01); 2.3.3 Ellipticine and Analogs; 2.3.4 |
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Acronycine and Analogs; 2.3.5 Colchicine and Analogs |
2.3.6 Ukrain2.4 Alkaloids Used for MDR Reversal; 2.4.1 Cinchona Alkaloids; 2.4.2 Dofequidar Fumarate (MS-209); 2.5 Alkaloids Used for Cancer Prevention; 2.6 Conclusions; 2.7 Acknowledgments; 3 Alkaloids and the Bitter Taste; 3.1 Introduction; 3.2 The Bitter Taste Chemoreception Mechanism; 3.3 Bitter Alkaloids in Food; 3.4 The Bitter Taste of Alkaloids in Other Drugs and Poisons; 3.5 Alkaloids and Taste in Insects; 3.6 The Bitter Taste of Alkaloids: Should We Avoid, Mask, or Understand?; 3.7 Acknowledgments; 4 Capsaicin and Capsaicinoids; 4.1 Introduction |
4.2 What Is an Alkaloid? Is Capsaicin an Alkaloid?4.3 Diversity, Biosynthesis, and Metabolism of Capsaicinoids; 4.4 Quantization of Capsaicinoids and Their Distribution in Chili Pepper; 4.5 Isolation and Synthesis of Capsaicin; 4.6 TRV1 as the Biological Target of Capsaicin and the Ecological Raison d'être of Capsaicinoids: A Molecular View; 4.7 Naturally Occurring Analogs and Antagonists of Capsaicin and Endogenous Vanilloids; 4.8 Structure-Activity Relationships of Capsaicinoids; 4.9 Molecular Gastronomy of Hot Food; 4.9.1 Biomedical Relevance of Capsaicin-Induced Trigeminal Responses |
4.9.2 Effect of Capsaicin on Taste4.9.3 Gustatory Sweating; 4.9.4 Gustatory Rhinitis; 4.9.5 Hot Food Mitridatism; 4.9.6 Effect of Capsaicin on Digestion; 4.9.7 Capsaicin and Stomach Cancer; 4.9.8 The Effect of Age and Sex on the Sensitivity to Capsaicin; 4.9.9 Capsaicin as a Slimming Agent; 4.9.10 Quenching Capsaicin; 4.9.11 Chilies and Olive Oil; 4.9.12 Who Should Avoid Chilies?; 4.9.13 How can the Pungency of Chilies be Moderated?; 4.9.14 Psychology of Pepper Consumption; 4.10 Conclusions; 4.11 Acknowledgments; 5 Glycosidase-Inhibiting Alkaloids: Isolation, Structure, and Application |
5.1 Introduction |
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Sommario/riassunto |
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This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis.A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry. |
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2. |
Record Nr. |
UNINA9910766890103321 |
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Autore |
Ingham Michael (Michael Anthony) |
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Titolo |
Anglo-American Stage and Screen Drama : The Post-Democratic World Order / / by Mike Ingham |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2024 |
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ISBN |
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Edizione |
[1st ed. 2024.] |
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Descrizione fisica |
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1 online resource (293 pages) |
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Disciplina |
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Soggetti |
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Theater - History |
Performing arts |
Theater |
Motion pictures |
Television broadcasting |
Motion picture acting |
Cultural policy |
Popular culture |
Contemporary Theatre and Performance |
Theatre and Performance Arts |
Film and Television Studies |
Screen Performance |
Cultural Policy and Politics |
Popular Culture |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Introduction:Anglophone Drama in a Post-Democratic, Post-Truth World -- Chapter 1. Western Theatre as Sociopolitical Forum—A Short History -- Chapter 2. Progressive Western Cinema -- Chapter 3. Case-study Films and Plays from the First Decade -- Chapter 4. Case-study Films and Plays from the First Decade -- Chapter 5. Case-study Films and Plays from the Second Decade.-Chapter 6. Case-study Films and Plays from the Second Decade -- Conclusion: Progressive Drama and |
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Sommario/riassunto |
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Anglo-American Stage and Screen Drama analyses and discusses the contemporary role of stage and screen drama as a critical forum for progressive thinking in an increasingly polarised geopolitical world. The book addresses the cultural politics of socially engaged 21st century stage plays and films, and makes the case for drama as a sociopolitical forum, in which the complex and contentious issues that confront society can be explored and debated. It conceives of Anglophone political drama as a significant intervention in today’s culture wars, representing the latter as a convenient distraction from the ongoing depredations of neoliberalism. In the main part of the book selected case-study plays and films from each of the first two decades illustrate drama’s capacity to influence critical debate on social justice issues. All of the case-study texts under discussion express a powerful aesthetics of resistance to right-wing ideology, and promote inclusive and enlightened values. This broader orientation underlines drama’s role as a channel for critical agency in today’s putative post-socialist, post-democratic climate. Mike Ingham is Adjunct Professor of English Studies in the English Department at The Chinese University of Hong Kong and a dedicated tertiary teacher and former teacher-trainer. His research interests include stage and screen drama, Shakespeare studies, Hong Kong literature in English, and drama in education. Mike is also a founder member of Theatre Action, a Hong Kong-based drama group specialising in action research on literary dramatic texts. Previous monograph publications include Staging Fictions - The Prose Fiction Stage Adaptation as Social Allegory (2004), Hong Kong - A Cultural and Literary History (2007), Stage-play and Screen-play: The Intermediality of Theatre and Cinema (2017) and The Intertextuality and Intermediality of theAnglophone Popular Song (2022). He has also produced journal articles and book chapters on adaptation for stage and screen, early modern drama, documentary and feature film in Asian and Western contexts, and drama pedagogy. |
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