1.

Record Nr.

UNINA9910144118403321

Autore

Nakamoto Kazuo <1922->

Titolo

Drug-DNA interactions [[electronic resource] ] : structures and spectra / / Kazuo Nakamoto, Masamichi Tsuboi, Gary D. Strahan

Pubbl/distr/stampa

Hoboken, N.J., : John Wiley & Sons, c2008

ISBN

1-281-81450-4

9786611814502

0-470-37061-0

0-470-36916-7

Descrizione fisica

1 online resource (396 p.)

Altri autori (Persone)

TsuboiMasamichi <1925->

StrahanGary D

Disciplina

572.8/6

Soggetti

DNA-drug interactions - Research - Methodology

DNA - Spectra

Drugs - Spectra

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

DNA structures and spectra -- Intercalating drugs -- Groove-binding drugs -- Covalent bonding drugs -- Strand-breaking drugs -- Metal-containing drugs.

Sommario/riassunto

Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear d