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Record Nr. |
UNINA9910144093303321 |
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Titolo |
Defining optimal immunotherapies for type 1 diabetes [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode] |
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Pubbl/distr/stampa |
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London, : Novartis Foundation, 2008 |
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ISBN |
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1-281-84052-1 |
9786611840525 |
0-470-69740-7 |
0-470-69741-5 |
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Descrizione fisica |
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1 online resource (224 p.) |
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Collana |
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Novartis Foundation symposium ; ; v. 292 |
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Disciplina |
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Soggetti |
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Diabetes - Immunotherapy |
Diabetes - Treatment |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Defining Optimal Immunotherapies for Type 1 Diabetes; Contents; Participants; Chair's introduction; Pancreatic pathology in type 1 diabetes in human; The b cell population in type 1 diabetes; Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation; Resuscitating adaptive Tregs with combination therapies?; Cytotoxic T cell mechanisms of b cell destruction in non-obese diabetic mice; Type 1 diabetes: chronic progressive autoimmune disease; Current and past prevention and intervention trials in type 1 diabetes |
CD8 and cytotoxic T cells in type 1 diabetesGeneral discussion I; General discussion II; Genetic and therapeutic control of diabetogenic CD8+ T cells; General discussion III; Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of b cell mass; Immune markers of disease and therapeutic intervention in type 1 diabetes; Re-establishing immune tolerance in type 1 diabetes via regulatory T cells; Translating mucosal antigen based prevention of autoimmune diabetes to human; Closing remarks; Contributor index; Subject index |
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