Proton passage across cell membranes

• Record Nr.: UNINA9910144012503321
• Pubbl/distr/stampa: Chichester, Sussex, U.K. ; ; New York, : Wiley, 1988
• ISBN: 1-282-12234-7; 9786612122347; 0-470-51369-1; 0-470-51370-5
• Descrizione fisica: 1 online resource (280 p.)
• Collana: Ciba Foundation symposium ; ; 139
• Altri autori (Persone): BockGregory; MarshJoan
• Disciplina: 574.87/5
• Soggetti: Biological transport; Protons; Cell membranes
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Proceedings of the Symposium on Proton Passage across Cell Membranes, held at the Ciba Foundation, London, 9-11 Feb. 1988.; Edited by Gregory Bock and Joan Marsh.; "A Wiley-Interscience publication."
• Nota di bibliografia: Includes bibliographies and indexes.
• Nota di contenuto: PROTON PASSAGE ACROSS CELL MEMBRANES; Contents; Participants; Introduction; Movement of acid equivalents across the mammalian smooth muscle cell rnem brane; Regulation of intracellular pH in cardiac muscle; Ionic mechanisms of intracellular pH regulation in the nervous system; Differential role of cation and anion exchange in lymphocyte pH regulation; General discussion I; Role of monocarboxylate transport in the regulation of intracellular pH of renal proximal tubule cells; Mechanisms of basolateral base transport in the renal proximal tubule; Electrogenic proton transport by intercalated cells of tight urinary epitheliaEpithelial pH and ion transport regulation by proton pumps and exchangers; General discussion II; Proton channels in snail neurons studied with surface pH glass microelectrodes; General discussion III; Proton-induced transformation in gating and selectivity of the calcium channel in neurons; Aldosterone-controlled linkage between Na+/H+- ; exchange and K+ channels in fused renal epithelial cells; Extracellular pH and stimulated neurons; General discussion IV; Structural properties of the proton translocating complex of the clathrin-coated vesicleGeneral discussion V; Summary; Index of contributors; Subject index
• Sommario/riassunto: Regulation of intracellular pH is vital to all living cells. This symposium covers the control of pH in muscle and nerve cells and the different mechanisms of acid transport across epithelial and other cell membranes. Papers describe the development and application of microelectrodes and various techniques in molecular biology to the study of the mechanisms of protein transport. Also discusses the significance of pH regulation for the action of hormones and growth factors.