1.

Record Nr.

UNINA9910144012303321

Titolo

Carbohydrate recognition in cellular function [[electronic resource]]

Pubbl/distr/stampa

Chichester [England] ; ; New York, : Wiley, 1989

ISBN

1-282-34761-6

9786612347610

0-470-51382-9

0-470-51383-7

Descrizione fisica

1 online resource (306 p.)

Collana

Ciba Foundation symposium ; ; 145

Altri autori (Persone)

BockGregory

HarnettSara

Disciplina

574.87

574.876

599.019248

Soggetti

Cell receptors

Carbohydrates

Cellular recognition

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Carbohydrate Recognition in Cellular Function, held at the Ciba Foundation, London, 15-17 November 1988"--P v.

"Editors: Gregory Bock (organizer) and Sara Harnett"--p v.

"A Wiley-Interscience publication."

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

CARBOHYDRATE RECOGNITION IN CELLULAR FUNCTION; Contents; Introduction; Oligosaccharide-protein interactions: a three-dimensional view; Multifunctional glycoprotein receptors for insulin and the insulin-like growth factors; Multiple subfamilies of carbohydrate recognition domains in animal lectins; Glycoprotein oligosaccharides as recognition structures; Binding modes of mammalian hepatic Gal/GalNAc receptors; General discussion I : Two human lysosomal membrane glycoproteins; Nucleoplasmic and cytoplasmic glycoproteins

Bioactive ganglioside-mediated carbohydrate recognition in coupling with ecto-protein phosphorylationRole of carbohydrates in receptor-mediated fertilization in mammals; Families of neural adhesion



molecules; Structural and biological properties of the carbohydrate units of nervous tissue glycoproteins; Carbohydrate recognition in neuronal development: structure and expression of surface oligosaccharides and B-galactoside-binding lectins; General discussion II : Expression of developmentally regulated carbohydrates; Function and pathology of the sugar chains of human immunoglobulin G

The role of oligosaccharides in modifying protein functionLeukosialin, a major sialoglycoprotein defining leucocyte differentiation; Final general discussion : The diversity of N-linked oligosaccharides on human immunodeficiency virus; Chairman's summing-up; Index of contributors; Subject index

Sommario/riassunto

Contributors to this volume explore the role of carbohydrates in communication between cells of multicellular organisms. Topics covered include the thermodynamics and spatial restrictions of oligosaccharide-protein interactions, the role of carbohydrates in recognition and as components of cell adhesion molecules, and abnormal glycosylation in several disease states.