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Record Nr. |
UNINA9910144011303321 |
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Titolo |
Telomeres and telomerase [[electronic resource] /] / [editors, Derek J. Chadwick and Gail Cardew] |
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Pubbl/distr/stampa |
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Chichester, England ; ; New York, : John Wiley & Sons, 1997 |
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ISBN |
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1-282-34806-X |
9786612348068 |
0-470-51543-0 |
0-470-51544-9 |
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Descrizione fisica |
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1 online resource (252 p.) |
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Collana |
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Ciba Foundation symposium ; ; 211 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Telomere |
Telomerase |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Symposium held at Ciba Foundation, Feb. 25-27, 1997. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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TELOMERES AND TELOMERASE; Contents; Participants; Introduction; The telomere and telomerase: how do they interact?; Telomerase and the chromosome end replication problem; General discussion I; The role of the EST genes in yeast telomere replication; Drosophila telornere elongation; General discussion I1; Raplp and telomere length regulation in yeast; Chromatin and ageing in yeast and in mammals; The limited reproductive life span of normal human cells in culture; Human ageing and telorneres; General discussion I11; Telomerase assays in the diagnosis and prognosis of cancer |
Mouse models for the study of telomeraseGenetic control of telomerase and replicative senescence in human and rodent cells; Repair and processing events at DNA ends; Telomeres in the haemopoietic system; Final general discussion; Summary; Index of contributors; Subject index |
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Sommario/riassunto |
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Telomeres and Telomerase Chairman: Sydney Brenner 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and |
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