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Record Nr. |
UNINA9910143720003321 |
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Titolo |
Epithelial anion transport in health and disease [[electronic resource] ] : the role of the SLC26 transporters family |
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Pubbl/distr/stampa |
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Chichester, U.K., : John Wiley & Sons, 2006 |
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ISBN |
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1-280-51891-X |
9786610518913 |
0-470-02957-9 |
0-470-02956-0 |
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Descrizione fisica |
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1 online resource (285 p.) |
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Collana |
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Novartis Foundation Symposium ; ; 273 |
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Disciplina |
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Soggetti |
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Epithelial cells |
Carrier proteins |
Ion channels |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Cover; Contents; Chair's introduction; Overview of the SLC26 family and associated diseases; Discussion; Individual characteristics of members of the SLC26 family in vertebrates and their homologues in insects; Discussion; Sulfate transport by SLC26 transporters; Discussion; Sugar transport by members of the SLC26 superfamily; Discussion; SLC26A3 and congenital chloride diarrhoea; Discussion; Expression, regulation and the role of SLC26 C1/HCO exchangers in kidney and gastrointestinal tract; Discussion |
Anion exchangers in flux: functional differences between human and mouse SLC26A6 polypeptidesDiscussion; Physiology of electrogenic SLC26 paralogues; Discussion; Role of SLC26-mediated C1/base exchange in proximal tubule NaCl transport; Discussion; SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion; Discussion; Regulatory interaction between CFTR and the SLC26 transporters; Discussion; Insights from a transgenic mouse model on the role of SLC26A2 in health and disease; Discussion |
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New insights into the role of pendrin (SLC26A4) in inner ear fluid homeostasisDiscussion; The renal physiology of pendrin (SLC26A4) and its role in hypertension; Discussion; Interaction of prestin (SLC26A5) with monovalent intracellular anions; Discussion; Final discussion; Index of contributors; Subject index |
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Sommario/riassunto |
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Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological functions since mutations in several members are linked to a variety of diseases. This book describes the properties of this family in detail, with contributions from the leading global researchers in the field. Complementary views from experts on ot |
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2. |
Record Nr. |
UNINA9910692002803321 |
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Titolo |
Foreign assistance [[electronic resource] ] : sustained efforts needed to help Southern Africa recover from food crisis : report to the ranking minority member, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate / / United States General Accounting Office |
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Pubbl/distr/stampa |
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Washington, D.C. : , : U.S. General Accounting Office, , [2003] |
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Soggetti |
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Economic assistance, American - Africa, Southern |
Food supply - Africa, Southern |
Africa, Southern Economic conditions |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from title screen (viewed on Oct. 23, 2003). |
"June 2003." |
Paper version available from: General Accounting Office, 441 G St., NW, Rm. LM, Washington, D.C. 20548. |
"GAO-03-644." |
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Nota di bibliografia |
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Includes bibliographical references. |
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