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1. |
Record Nr. |
UNINA9910459673503321 |
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Titolo |
Quality practices for regulated non-clinical research and development [[electronic resource] /] / UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases |
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Pubbl/distr/stampa |
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Geneva, : WHO on behalf of the Special Programme for Research and Training in Tropical Diseases, c2009 |
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ISBN |
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1-282-76077-7 |
9786612760778 |
92-4-068530-8 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (327 p.) |
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Disciplina |
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Soggetti |
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Laboratories - Standards |
Laboratories - Technique |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Handbook : Good Laboratory Practice (GLP). |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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CONTENTS; 1. INTRODUCTION TO THE WHO/TDR HANDBOOK ON GLP; GENERAL INTRODUCTION; INTRODUCTION TO GLP AND ITS APPLICATION; 2. GOOD LABORATORY PRACTICE TRAINING; INTRODUCTION; THE FUNDAMENTAL POINTS OF GLP; RESOURCES; CHARACTERISATION; RULES FOR PERFORMING STUDIES; RESULTS - RAW DATA AND DATA COLLECTION; QUALITY ASSURANCE UNIT; 3. STEPWISE IMPLEMENTATION OF GLP; INTRODUCTION; IMPLEMENTATION AS A PROJECT; STEPWISE IMPLEMENTATION OF GLP REQUIREMENTS; ANNEXES: OECD SERIES ON PRINCIPLES OF GOOD LABORATORY PRACTICE AND COMPLIANCE MONITORING; I. OECD PRINCIPLES ON GOOD LABORATORY PRACTICE |
II. GUIDANCE FOR GLP MONITORING AUTHORITIES: REVISED GUIDES FOR COMPLIANCE MONITORING PROCEDURES FOR GOOD LABORATORY PRACTICEIII. GUIDANCE FOR GLP MONITORING AUTHORITIES: REVISED GUIDANCE FOR THE CONDUCT OF LABORATORY INSPECTIONS AND STUDY AUDITS; IV . QUALITY ASSURANCE AND GLP; V . COMPLIANCE OF LABORATORY SUPPLIERS WITH GLP PRINCIPLES; VI . THE APPLICATION OF THE GLP PRINCIPLES TO FIELD STUDIES; VII . THE APPLICATION OF |
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THE GLP PRINCIPLES TO SHORT TERM STUDIES; VIII . THE ROLE AND RESPONSIBILITIES OF THE STUDY DIRECTOR IN GLP STUDIES |
IX . GUIDANCE FOR GLP MONITORING AUTHORITIES: GUIDANCE FOR THE PREPARATION OF GLP INSPECTION REPORTSX . THE APPLICATION OF THE PRINCIPLES OF GLP TO COMPUTERISED SYSTEMS; XI . THE ROLE AND RESPONSIBILITIES OF THE SPONSOR IN THE APPLICATION OF THE PRINCIPLES OF GLP; XII . REQUESTING AND CARRYING OUT INSPECTIONS AND STUDY AUDITS IN ANOTHER COUNTRY; XIII . THE APPLICATION OF THE OECD PRINCIPLES OF GLP TO THE ORGANISATION AND MANAGEMENT OF MULTI-SITE STUDIES; XIV . THE APPLICATION OF THE PRINCIPLES OF GLP TO IN-VITRO STUDIES |
XV . ESTABLISHMENT AND CONTROL OF ARCHIVES THAT OPERATE IN COMPLIANCE WITH THE PRINCIPLES OF GLP |
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Sommario/riassunto |
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Good laboratory practices (GLP) are the recognized rules governing the conduct of non-clinical safety studies. They ensure the quality, integrity and reliability of the study data. This handbook is designed as an aid for those countries wishing to upgrade their laboratories to GLP status. Based on the Organisation for Economic Cooperation and Development (OECD) principles of GLP, the handbook provides laboratories and trainers in disease endemic countries with the necessary technical information for implementing GLP programs. The material in the handbook is presented in a clear and informative |
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2. |
Record Nr. |
UNINA9910143208903321 |
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Autore |
Doyle James F. <1951-> |
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Titolo |
Modern experimental stress analysis [[electronic resource] ] : completing the solution of partially specified problems / / James F. Doyle |
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Pubbl/distr/stampa |
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Hoboken, NJ, : Wiley, 2004 |
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ISBN |
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1-280-27133-7 |
9786610271337 |
0-470-30025-6 |
0-470-86158-4 |
0-470-86157-6 |
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Descrizione fisica |
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1 online resource (440 p.) |
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Disciplina |
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Soggetti |
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Structural analysis (Engineering) |
Strains and stresses |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [413]-422) and index. |
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Nota di contenuto |
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MODERN EXPERIMENTAL STRESS ANALYSIS; Contents; Preface; Notation; Introduction; 1 Finite Element Methods; 1.1 Deformation and Strain; 1.2 Tractions and Stresses; 1.3 Governing Equations of Motion; 1.4 Material Behavior; 1.5 The Finite Element Method; 1.6 Some Finite Element Discretizations; 1.7 Dynamic Considerations; 1.8 Geometrically Nonlinear Problems; 1.9 Nonlinear Materials; 2 Experimental Methods; 2.1 Electrical Filter Circuits; 2.2 Digital Recording and Manipulation of Signals; 2.3 Electrical Resistance Strain Gages; 2.4 Strain Gage Circuits; 2.5 Motion and Force Transducers |
2.6 Digital Recording and Analysis of Images 2.7 Moiré Analysis of Displacement; 2.8 Holographic Interferometry; 2.9 Photoelasticity; 3 Inverse Methods; 3.1 Analysis of Experimental Data; 3.2 Parametric Modeling of Data; 3.3 Parameter Identification with Extrapolation; 3.4 Identification of Implicit Parameters; 3.5 Inverse Theory for Ill-Conditioned Problems; 3.6 Some Regularization Forms; 3.7 Relocation |
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of Data onto a Grid Pattern; 3.8 Discussion; 4 Static Problems; 4.1 Force Identification Problems; 4.2 Whole-Field Displacement Data; 4.3 Strain Gages; 4.4 Traction Distributions |
4.5 Nonlinear Data Relations 4.6 Parameter Identification Problems; 4.7 Choosing the Parameterization; 4.8 Discussion; 5 Transient Problems with Time Data; 5.1 The Essential Difficulty; 5.2 Deconvolution using Sensitivity Responses; 5.3 Experimental Studies; 5.4 Scalability Issues: Recursive Formulation; 5.5 The One-Sided Hopkinson Bar; 5.6 Identifying Localized Stiffness and Mass; 5.7 Implicit Parameter Identification; 5.8 Force Location Problems; 5.9 Discussion; 6 Transient Problems with Space Data; 6.1 Space-Time Deconvolution; 6.2 Preliminary Metrics; 6.3 Traction Distributions |
6.4 Dynamic Photoelasticity 6.5 Identification Problems; 6.6 Force Location for a Shell Segment; 6.7 Discussion; 7 Nonlinear Problems; 7.1 Static Inverse Method; 7.2 Nonlinear Structural Dynamics; 7.3 Nonlinear Elastic Behavior; 7.4 Elastic-Plastic Materials; 7.5 Nonlinear Parameter Identification; 7.6 Dynamics of Cracks; 7.7 Highly Instrumented Structures; 7.8 Discussion; Afterword; References; Index |
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Sommario/riassunto |
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All structures suffer from stresses and strains caused by factors such as wind loading and vibrations. Stress analysis and measurement is an integral part of the design and management of structures, and is used in a wide range of engineering areas. There are two main types of stress analyses - the first is conceptual where the structure does not yet exist and the analyst has more freedom to define geometry, materials, loads etc - generally such analysis is undertaken using numerical methods such as the finite element method. The second is where the structure (or a prototype) exists, and so s |
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3. |
Record Nr. |
UNISA996205997503316 |
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Titolo |
Arion |
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Pubbl/distr/stampa |
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Moskva, : Izd-vo Rusanova, 1994- |
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ISSN |
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Disciplina |
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Soggetti |
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Russian poetry - 20th century |
Russian poetry - History and criticism |
Poetry, Modern |
Russian poetry |
Criticism, interpretation, etc. |
Periodicals. |
Translations. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Periodico |
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Note generali |
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