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Record Nr. |
UNINA9910143128803321 |
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Autore |
Cooke Roger M. <1946-> |
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Titolo |
Uncertainty modeling in dose response [[electronic resource] ] : bench testing environmental toxicity / / Roger M. Cooke |
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Pubbl/distr/stampa |
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ISBN |
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1-282-69103-1 |
9786612691034 |
0-470-48140-4 |
0-470-48139-0 |
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Descrizione fisica |
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1 online resource (246 p.) |
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Collana |
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Statistics in Practice ; ; v.74 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Environmental toxicology - Mathematical models |
Toxicology - Dose-response relationship - Mathematical models |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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UNCERTAINTY MODELING IN DOSE RESPONSE; CONTENTS; Acknowledgments; Contributors; Introduction; 1 Analysis of Dose-Response Uncertainty Using Benchmark Dose Modeling; Comment: The Math/Stats Perspective on Chapter 1: Hard Problems Remain; Comment: EPI/TOX Perspective on Chapter 1: Re-formulating the Issues; Comment: Regulatory/Risk Perspective on Chapter 1: A Good Baseline; Comment: A Question Dangles; Comment: Statistical Test for Statistics-as-Usual Confidence Bands; Response to Comments |
2 Uncertainty Quantification for Dose-Response Models Using Probabilistic Inversion with Isotonic Regression: Bench Test ResultsComment: Math/Stats Perspective on Chapter 2: Agreement and Disagreement; Comment: EPI/TOX Perspective on Chapter 2: What Data Sets Per se Say; Comment: Regulatory/Risk Perspective on Chapter 2: Substantial Advances Nourish Hope for Clarity?; Comment: A Weakness in the Approach?; Response to Comments; 3 Uncertainty Modeling in Dose Response Using Nonparametric Bayes: Bench Test Results; Comment: Math/Stats Perspective on Chapter 3: Nonparametric Bayes |
Comment: EPI/TOX View on Nonparametric Bayes: Dosing PrecisionComment: Regulator/Risk Perspective on Chapter 3: Failure to |
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