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Record Nr. |
UNINA9910143100003321 |
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Autore |
Lütolf-Carroll Constance <1955-> |
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Titolo |
From innovation to cash flows [[electronic resource] ] : value creation by structuring high technology alliances / / Constance Lütolf-Carroll, Antti Pirnes |
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Pubbl/distr/stampa |
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Hoboken, NJ, : Wiley, c2009 |
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ISBN |
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1-282-68544-9 |
9786612685446 |
1-118-27316-8 |
0-470-47357-6 |
0-470-47367-3 |
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Descrizione fisica |
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1 online resource (643 p.) |
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Collana |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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New business enterprises |
Entrepreneurship |
Cash flow |
Intellectual property |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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From Innovation to Cash Flows: Value Creation by Structuring High Technology Alliances; Contents; Foreword; Preface; A NOTE TO TEACHERS WHO WISH TO ADOPT THIS BOOK; Acknowledgments; Part I: Creativity and the Roles of the Inventor, Innovator, and Entrepreneur; Chapter 1: Creativity and the Entrepreneurial Process; Chapter 2: Protecting Your Invention; Part II: Building Business Models; Chapter 3: Understanding Strategy Basics; Chapter 4: Strategies to Grow, Restructure, or Harvest Your Business; Chapter 5: Key Elements of a Business Model; Part III: Crafting Strategic Alliances |
Chapter 6: Introduction to Strategic AlliancesChapter 7: Managing Alliances; Chapter 8: How Alliances Complete the Value Chain in Biotechnology and Pharmaceutical Business Models; Part IV: |
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Understanding Legal Agreements; Chapter 9: Contract Law, Key Legal Agreements for Business, and Incorporation Issues; Chapter 10: Investment Agreements; Chapter 11: The Intellectual Property Landscape; Chapter 12: The Basics about Patents; Chapter 13: General Patenting Strategies in High-Technology Industries; Chapter 14: Navigating Technology License Agreements |
Part V: Competitive Intelligence and Due DiligenceChapter 15: Competitive Intelligence and Patent Searching; Chapter 16: Due Diligence; Part VI: Valuing Company Cash Flows; Chapter 17: Valuation Using Discounted Cash Flow; Chapter 18: Valuation Using Market Multiples and Comparable Deal Transactions; Chapter 19: Venture Capital Method of Valuation; Chapter 20: Valuing and Structuring High Technology Strategic Alliances; Conclusion; THE BASIC BROTH OF BUSINESS; BUILDING THE HIGH-TECHNOLOGY BUSINESS VENTURE; Notes; References; About the Authors; About the Contributors; About The Web Site; Index |
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Sommario/riassunto |
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Praise for From Innovation to Cash Flows ""Critically important topics for all entrepreneurs, new and experienced. Collaboration, intellectual property, and funding are described with depth and thoughtfulness. From Innovation to Cash Flows provides both the theoretical structure and the rich examples to serve as a great reference. Not to be missed!""-Cheryl A. Fragiadakis, Head of Technology Transfer and Intellectual Property Management, Lawrence Berkeley National Laboratory ""From Innovation to Cash Flows is a unique book that covers many of the esse |
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2. |
Record Nr. |
UNINA9910298335203321 |
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Titolo |
Molecular Genetics of Dysregulated pH Homeostasis / / edited by Jen-Tsan Ashley Chi |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
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ISBN |
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Edizione |
[1st ed. 2014.] |
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Descrizione fisica |
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1 online resource (158 p.) |
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Disciplina |
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571.6 |
599935 |
610 |
611.01816 |
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Soggetti |
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Human genetics |
Cytology |
Medicine |
Human Genetics |
Cell Biology |
Biomedicine, general |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of eah chapters and index. |
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Nota di contenuto |
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Molecular Genetics of Acid Sensing and Response -- Part I: Sensing Acidity -- The molecular mechanism of cellular sensing of acidity -- The Molecular Basis of Sour Sensing in Mammals -- Function and Signaling of the pH-sensing G protein-coupled receptors in physiology and diseases -- Part II: Response to Acidity -- The MondoA-TXNIP checkpoint couples the acidic tumor microenvironment to cell metabolism -- Regulation of Renal Glutamine Metabolisms during Metabolic Acidosis -- Extracellular acidosis and cancer -- The genomic analysis of cellular responses and adaptions to extracellular acidosis -- Index. |
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Sommario/riassunto |
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Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological function at every level, including protein folding, enzymatic activities and proliferation, and cell death. Therefore, maintaining the pH |
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homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in scientific literature and in medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events, and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases including cancer, stroke, myocardial infarction, diabetes, and renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and respond to acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanisms and cellular responses to pH alterations in both physiological (taste, pain) and pathological (ischemia and cancers) settings. Furthermore, the authors present a broad spectrum of investigative approaches to cellular response to acidosis in a wide variety of human diseases. |
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