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Record Nr. |
UNINA9910142501603321 |
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Titolo |
Cellular aspects of HIV infection [[electronic resource] /] / edited by Andrea Cossarizza, David Kaplan |
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Pubbl/distr/stampa |
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New York, : Wiley-Liss, c2002 |
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ISBN |
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1-280-36636-2 |
9786610366361 |
0-470-23280-3 |
0-471-45915-1 |
0-471-22393-X |
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Descrizione fisica |
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1 online resource (474 p.) |
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Collana |
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Cytometric cellular analysis |
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Altri autori (Persone) |
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CossarizzaAndrea <1958-> |
KaplanDavid <1952-> |
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Disciplina |
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616.97/9207 |
616.9792 |
616.979207 |
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Soggetti |
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AIDS (Disease) - Cytopathology |
AIDS (Disease) - Molecular aspects |
Flow cytometry |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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CELLULAR ASPECTS OF HIV INFECTION; CONTENTS; Preface; Contributors; Part I MOLECULES; 1 HIV and Molecular Biology of the Virus-Host Interplay; 2 Telomere Length, CD28(-) T Cells, and HIV Disease Pathogenesis; 3 Immune Dysregulation and T-Cell Activation Antigens in HIV Infection; 4 Quantification of HIV/SIV Coreceptor Expression; Part II CELLS; 5 B Cells in the Line of Sight of HIV-1; 6 Cytotoxic T-Cell (CTL) Function in HIV Infection; 7 Analysis of the a/b T-Cell Receptor Repertoire in HIV Infection; 8 Gamma-Delta (gd) T Cells and HIV-1 Infection |
9 Natural Killer Cells in HIV Infection and Role in the Pathogenesis of AIDS 10 Alveolar Macrophages; 11 Dendritic Cells Ferry HIV-1 from Periphery into Lymphoid Tissues; Part III PROCESSES; 12 Homeostasis |
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and Restoration of the Immune System in HAART-Treated HIV-Infected Patients: Implications of Apoptosis; 13 Mitochondria Functionality During HIV Infection; 14 Multiple Roles of Cytokines in HIV Infection, Replication, and Therapy; Part IV TECHNOLOGIES; 15 The Use of Peptide/MHC Tetramers to Visualize, Track, and Characterize Class I-Restricted Anti-HIV T-Cell Response |
16 Tagging of HIV with Green Fluorescent Protein 17 Flow Cytometric Analysis of Cells from Persons with HIV-1 Disease by Enzymatic Amplification Staining; 18 Antigen-Specific Cytokine Responses in HIV Disease; Part V ORGANISMS; 19 Chimeric Models of SCID Mice Transplanted with Human Cells: The Hu-PBL-SCID Mouse and Its Use in AIDS Research; 20 Immune Reconstitution of the CD4 T-Cell Compartment in HIV Infection; 21 New Perspectives in Antiretroviral Therapy of HIV Infection; Index |
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Sommario/riassunto |
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Cellular Aspects of HIV Infection provides a highly readable, detailed overview of the state of the art in modern HIV research at the cellular level. This volume brings together renowned experts who have provided concise, synthetic treatments of the biology of HIV infection. It presents these descriptions and analyses with particular attention to the techniques of flow cytometry that have allowed us to not only observe the course of HIV infection and the immune system's response to it, but have also increased our ability to treat patients and understand their response to therapy.The bo |
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2. |
Record Nr. |
UNINA9910141294003321 |
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Autore |
Nolop Bruce <1950-> |
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Titolo |
The essential CFO : a corporate finance playbook / / Bruce Nolop |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, Inc., 2012 |
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ISBN |
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9786613619303 |
9781119205036 |
1119205034 |
9781280589478 |
1280589477 |
9781118226896 |
1118226895 |
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Edizione |
[1st edition] |
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Descrizione fisica |
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1 online resource (381 p.) |
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Collana |
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Classificazione |
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Disciplina |
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Soggetti |
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Chief financial officers |
Corporations - Finance - Management |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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The Essential CFO; Contents; Introduction; PART I: STRATEGY; Chapter 1: Articulating a Strategic Plan; Business Objectives; Strategic Themes; Long-Term Financial Model; Total Shareholder Return; Capital Allocation Strategies; Acquisition Strategies; Target Shareholders; Elevator Pitch; Plan Revisions; Chapter 2: Communicating and Achieving Alignment; Consistency and Transparency; Incentive Compensation Programs; Investor Alignment; Analyst Relations; Investor Presentations; Company Website; Social Media; Media Relations; Potential Media Pitfalls; Coordinating Communications; Interview Formats |
Media Training Note; Chapter 3: Assessing Enterprise Risks; Enterprise Risk Management; Implementation of ERM; Risk Identification; Risk Quantification; Major Exposures; Mitigation Strategies; Rewarded versus Unrewarded Risks; Governance of ERM; CFO's Role in ERM; PART II: CAPITAL ALLOCATIONS; Chapter 4: Estimating the Cost of Capital; WACC Formula; Hurdle Rates; Risk Premiums; Acquisition Cost of Capital; Chapter 5: Prioritizing Capital Investments; Cash Flow |
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Projections; Investment Budget; Evaluating Projects; Categorizing Projects; Monitoring Projects; Pension Fund Contributions |
Chapter 6: Considering Dividends and Repurchases Dividend Policy Alternatives; Dividend Policy Considerations; Special Dividends; Dividend Declarations; Repurchase Considerations; Open Market Programs; Tender Offers; Retaining Strategic Cash; Cash Investment Policies; PART III: MERGERS AND ACQUISITIONS; Chapter 7: Identifying Acquisition Candidates; Rationale for Acquisitions; Adjacent Spaces; Portfolio Approach; Business Sponsor; Patience and Flexibility; Strategic Purpose; Types of Acquisitions; Note; Chapter 8: Evaluating Acquisition Candidates; Valuation Methodologies |
Standalone and Synergy Values Pro Forma Analyses; Acquirer's Stock Valuation; Risk Considerations; Chapter 9: Executing a Merger or Acquisition; Due Diligence; Business Plan; Financial Projections; Financing Plan; Price Negotiations; Contract Terms; Acquisition Integration; Note; Chapter 10: Executing Divestitures and Spinoffs; Divestiture Evaluations; Hiring Investment Bankers; Auction or Negotiated; Stock or Assets; Financing Conditions; Management Participation; Tax-Free Spinoffs; Split-Ups; Equity Carve-Outs; Chapter 11: Responding to Takeover Offers; Governance Policies |
Reviewing an Offer Conducting a Sale Process; Activist Shareholders; Going Private Transactions; PART IV: FUNDING; Chapter 12: Establishing Capital Structure Objectives; Leverage Targets; Leverage Criteria; Rating Agencies; Ratings Categories; Rating Agency Dialogues; Ratings Criteria; Informing Investors; Note; Chapter 13: Developing Financing Strategies; Financing Principles; Debt Financing; Equity Financing; Off Balance Sheet Financing; Debt Covenants; Debt Refinancing; Debt for Equity Swaps; Bankruptcy; Chapter 14: Ensuring Short-Term Liquidity; Bank Lines; Cash Planning |
Contingency Planning |
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Sommario/riassunto |
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Discover the power of the CFO's role in delivering shareholder value During the past decade, the CFO role has expanded dramatically in its breadth, complexity, and criticality. Filled with proven strategies, best practices, and keen insights, The Essential CFO describes how today's CFOs are responding to their expanded roles within both public and private companies. With straightforward and pragmatic guidance, author Bruce Nolop shows how CFOs are partnering with CEOs to deliver shareholder value by articulating a strategic plan, determining capital allocations, managing |
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