Organelle-specific pharmaceutical nanotechnology [[electronic resource] /] / edited by Volkmar Weissig, Gerard G.M. D'Souza

• Record Nr.: UNINA9910140835903321
• Pubbl/distr/stampa: Hoboken, NJ, : Wiley, 2010
• ISBN: 1-118-07434-3; 1-299-18614-9; 0-470-87578-X; 0-470-87577-1
• Descrizione fisica: 1 online resource (638 p.)
• Altri autori (Persone): WeissigVolkmar; D'SouzaGerard G. M
• Disciplina: 615/.19
• Soggetti: Pharmaceutical technology; Nanotechnology; Drug targeting
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di contenuto: ORGANELLE-SPECIFIC PHARMACEUTICAL NANOTECHNOLOGY; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: An Introduction to Subcellular Nanomedicine: Current Trends and Future Developments; CHAPTER 2: Delivery of Nanosensors to Measure the Intracellular Environment; CHAPTER 3: Cytoplasmic Diffusion of Dendrimers and Dendriplexes; CHAPTER 4: Endocytosis and Intracellular Trafficking of Quantum Dot-Ligand Bioconjugates; CHAPTER 5: Synthesis of Metal Nanoparticle-Based Intracellular Biosensors and Therapeutic Agents; CHAPTER 6: Subcellular Fate of Nanodelivery Systems; CHAPTER 7: Intracellular Fate of Plasmid DNA PolyplexesCHAPTER 8: Intracellular Traffi cking of Membrane Receptor-Mediated Uptake of Carbon Nanotubes; CHAPTER 9: Real-Time Particle Tracking for Studying Intracellular Transport of Nanotherapeutics; CHAPTER 10: Tracking Intracellular Polymer Localization Via Fluorescence Microscopy; CHAPTER 11: Can QSAR Models Describing Small-Molecule Xenobiotics Give Useful Tips for Predicting Uptake and Localization of Nanoparticles in Living Cells? And If Not, Why Not?; CHAPTER 12: Self-; Unpacking Gene Delivery Scaffolds; CHAPTER 13: Cellular Trafficking of DendrimersCHAPTER 14: Endolysosomolytically Active pH-Sensitive Polymeric Nanotechnology; CHAPTER 15: Uptake and Intracellular Dynamics of Proteins Internalized by Cell-Penetrating Peptides; CHAPTER 16: Cargo Transport by Teams of Molecular Motors: Basic Mechanisms for Intracellular Drug Delivery; CHAPTER 17: The Potential of Photochemical Internalization (PCI) for the Cytosolic Delivery of Nanomedicines; CHAPTER 18: Peptide-Based Nanocarriers for Intracellular Delivery of Biologically Active Proteins; CHAPTER 19: Organelle-Specific Pharmaceutical Nanotechnology: Active Cellular Transport of Submicro- and Nanoscale ParticlesCHAPTER 20: Subcellular Targeting of Virus-Envelope-Coated Nanoparticles; CHAPTER 21: Mitochondria-Targeted Pharmaceutical Nanocarriers; CHAPTER 22: Cell-Penetrating Peptides for Cytosolic Delivery of Biomacromolecules; CHAPTER 23: Therapeutic Nano-object Delivery to Subdomains of Cardiac Myocytes; CHAPTER 24: Design Parameters Modulating Intracellular Drug Delivery: Anchoring to Specific Cellular Epitopes, CarrierGeometry, and Use of Auxiliary Pharmacological Agents; CHAPTER 25: Uptake Pathways Dependent Intracellular Trafficking of DNA Carrying Nanodelivery SystemsCHAPTER 26: Cellular Interactions of Plasmon-Resonant Gold Nanorods; CHAPTER 27: Quantum Dot Labeling for Assessment of Intracellular Trafficking of Therapeutically Active Molecules; INDEX
• Sommario/riassunto: This book introduces and discusses the latest in biomedical research--Pharmaceutical Nanotechnology applied at the sub-cellular level.