1.

Record Nr.

UNINA9910703601403321

Titolo

Charcoal production, marketing, and use / / compiled by Forest Products Laboratory

Pubbl/distr/stampa

Madison, Wisconsin : , : United States Department of Agriculture, Forest Service, Forest Products Laboratory, , 1961

Descrizione fisica

1 online resource (iii, 137 pages) : illustrations, maps

Collana

Report ; ; no. 2213

Soggetti

Charcoal

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from title screen (viewed Feb. 26, 2015).

"Prepared in cooperation with the Lake States and Southeastern Experiment stations"--acknowledgment.

"July 1961."

Publication pre-dates Federal Depository Library Program (FDLP) item numbers. No FDLP item number has been assigned.

Nota di bibliografia

Includes bibliographical references (pages 127-135).



2.

Record Nr.

UNINA9910140620103321

Titolo

Vanilloid receptor TRPV1 in drug discovery : targeting pain and other pathological disorders / / edited by Arthur Gomtsyan, Connie R. Faltynek

Pubbl/distr/stampa

Hoboken, NJ, : Wiley, c2010

ISBN

9786612551598

9781282551596

1282551590

9780470588284

0470588284

9780470588277

0470588276

Edizione

[1st ed.]

Descrizione fisica

1 online resource (486 p.)

Altri autori (Persone)

GomtsyanArthur

FaltynekConnie R

Disciplina

615.783

615/.783

Soggetti

Analgesics

Drugs - Design

Nociceptors

Inflammation

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

VANILLOID RECEPTOR TRPV1 IN DRUG DISCOVERY; CONTENTS; PREFACE AND ACKNOWLEDGMENTS; FOREWORD; CONTRIBUTORS; PART I INTRODUCTION TO THE TRP CHANNELS; 1 TRP Channels and Human Diseases; 2 Role of TRP Channels in Pain: An Overview; 3 Biochemical Pharmacology of TRPV1: Molecular Integrator of Pain Signals; 4 TRPV1 Genetics; PART II ROLE FOR TRPV1 IN PAIN STATES; 5 TRPV1 and Inflammatory Pain; 6 Role of TRPV1 Receptors in Osteoarthritic Pain; 7 TRPV1 and Bone Cancer Pain; 8 TRPV1 in Visceral Pain and Other Visceral Disorders; 9 TRPV1 Receptors and Migraine

10 TRPV1 in Neuropathic Pain and Neurological and Neuropsychiatric



Disorders PART III TRPV1 ANTAGONISTS AND AGONISTS AS NOVEL ANALGESIC DRUGS; 11 Aryl-Urea Class and Related TRPV1 Antagonists; 12 2-Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists; 13 TRPV1 Agonist Approaches for Pain Management; PART IV ROLE FOR TRPV1 IN OTHER PHYSIOLOGICAL PROCESSES BESIDES PAIN TRANSMISSION; 14 The TRPV1 Channel in Normal Thermoregulation: What Have We Learned from Experiments Using Different Tools?; 15 The Role of TRPV1 in Respiratory Diseases; 16 The Role of TRPV1 in Diabetes; AFTERWORD

INDEX

Sommario/riassunto

Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low back pain, neuropathic pain, and cancer pain, some consider it ""the holy grail"" of pain management. This dedicated reference summarizes available data related to the potential therapeutic utility for TRPV1 ligands. With contributions from many of the world's leading experts on TRP channels, Vanilloid Receptor TRPV1