1.

Record Nr.

UNINA9910140555103321

Titolo

Mass spectrometry for microbial proteomics [[electronic resource] /] / edited by Haroun Shah and Saheer Gharbia

Pubbl/distr/stampa

Hoboken, N.J., : Wiley, 2010

ISBN

1-119-99192-7

1-282-65384-9

9786612653841

0-470-66549-1

0-470-66547-5

Descrizione fisica

1 online resource (535 p.)

Altri autori (Persone)

ShahHaroun N

GharbiaSaheer

Disciplina

572/.36

Soggetti

Microbial proteins - Spectra

Mass spectrometry

Proteomics - Methodology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

pt. 1. Microbial characterisation ; The transition from conventional methods to proteomics -- pt. 2. Proteomics tools and biomarker discovery -- pt. 3. Protein samples : preparation techniques -- pt. 4. Characterisation of microorganisms by pattern matching of mass spectral profiles and biomarker approaches requiring minimal sample preparation -- pt. 5. Targeted molecules and analysis of specific microorganisms -- pt. 6. Statistical analysis of 2D gels and analysis of mass spectral data -- pt. 7. DNA resequencing by MALDI-TOF-mass spectrometry and its application to traditional microbiological problems.

Sommario/riassunto

New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the



broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections that follow the general progression in which most microbiology laboratories are app