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1. |
Record Nr. |
UNINA9910139986703321 |
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Titolo |
Carbohydrate-based vaccines and immunotherapies [[electronic resource] /] / edited by Zhongwu Guo, Geert-Jan Boons |
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Pubbl/distr/stampa |
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Hoboken, N.J. ; ; Oxford, [UK], : Wiley, c2009 |
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ISBN |
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1-282-36851-6 |
9786612368516 |
0-470-47328-2 |
0-470-47327-4 |
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Descrizione fisica |
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1 online resource (436 p.) |
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Collana |
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Wiley series in drug discovery and development |
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Altri autori (Persone) |
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GuoZhongwu |
BoonsGeert-Jan |
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Disciplina |
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Soggetti |
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Carbohydrates - Immunology |
Vaccines |
Glycoconjugates - Immunology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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CARBOHYDRATE-BASED VACCINES AND IMMUNOTHERAPIES; CONTENTS; Preface; Contributors; 1 Glycobiology and Immunology; 1.1 Introduction; 1.2 Glycobiology; 1.2.1 Glycosylation-Is It Worth the Cost?; 1.2.2 Glycan Biosynthesis-A Dauntingly Complex Process; 1.2.3 Glycoproteins; 1.2.4 Lipid-Based Glycans; 1.2.5 Polysaccharides: Glycosaminoglycans and Bacterial Capsular Components; 1.3 The Immune System; 1.3.1 Introductory Comments; 1.3.2 Overview of the Immune System; 1.3.3 Glycoimmunobiology; 1.3.4 Interplay between Glycosylation and Sugars: a Two-Way Street; 1.4 Carbohydrate Antigens |
1.4.1 Carbohydrate Antigens in Humans1.4.2 Carbohydrates and Pathogens; 1.4.3 Carbohydrate-Based Vaccines; 1.4.4 Concluding Comments: Building on Success; Acknowledgment; References; 2 Preparation of Glycoconjugate Vaccines; 2.1 Introduction; 2.2 Capsular Polysaccharide-Protein Conjugates; 2.2.1 Haemophilus influenzae Type b; 2.2.2 Streptococcus pneumoniae; 2.2.3 Neisseria meningitidis; 2.2.4 Salmonella typhi Vi; 2.2.5 Group B Streptococcus; 2.2.6 Staphylococcus |
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aureus Types 5 and 8; 2.3 Lipopolysaccharide (LPS) and Lipooligosaccharide (LOS) Conjugates; 2.3.1 Escherichia coli O157 |
2.3.2 Vibrio cholerae O1 and O1392.3.3 Shigella dysenteriae Type 1, sonnei and flexneri 2a; 2.3.4 Neisseria meningitidis and Nontypeable Haemophilus influenzae; 2.4 Total Synthetic Glycoconjugate Vaccines; References; 3 Adjuvants for Protein- and Carbohydrate-Based Vaccines; 3.1 Introduction; 3.2 Initiation and Stimulation of Adaptive Responses; 3.3 "Old" Adjuvants and Formulations; 3.3.1 Aluminum; 3.3.2 Emulsions; 3.3.3 Saponins, QS21, and ISCOMS; 3.3.4 Liposomes and Microparticles; 3.3.5 Antigen/Formulation Targeting; 3.3.6 Induction of CD8 CTLs with Soluble Antigens |
3.4 Renaissance of Innate Immunity3.4.1 Toll-Like Receptors: Agonists and Roles; 3.4.2 Non-TLRs Innate Receptors; 3.4.3 Other Receptors Involved in Antigen Capture and Recognition; 3.5 From Basic Research to Practical Applications: Identification of New Adjuvants; 3.5.1 TLR Synthetic Agonists; 3.5.2 Combination of PRR Agonists; 3.6 Adjuvants for Carbohydrate-Based Vaccines; 3.6.1 Td and Ti B-Cell Responses; 3.6.2 Adjuvants for "Free" Polysaccharides (Ti Antigens); 3.6.3 Adjuvants for Glycoconjugate Vaccines (T-Dependent Antigens) |
3.7 Combinations of Adjuvants: Preclinical and Clinical Developments3.8 Immunomodulation of Existing Responses: Adjuvants for Therapeutic Vaccines; 3.9 Take Another Route; 3.9.1 Adjuvants for Mucosal Immunization; 3.9.2 Epidermal or Intradermal Routes; 3.10 Practical Aspects of Adjuvant Development; 3.10.1 Regulatory Aspects; 3.10.2 Safety versus Efficacy: Risk-Benefit Ratio; 3.11 Preclinical Models Used in Adjuvant Development; 3.11.1 Animal Models; 3.11.2 In vitro Models; 3.12 Conclusions and Perspectives; Acknowledgment; References; 4 Carbohydrate-Based Antibacterial Vaccines |
4.1 Introduction |
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Sommario/riassunto |
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The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of va |
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2. |
Record Nr. |
UNISALENTO991004258930907536 |
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Autore |
Mantegazza, Paolo <1831-1910> |
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Titolo |
Fisiologia del piacere / / di Paolo Mantegazza |
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Pubbl/distr/stampa |
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Milano : G. Bernardoni, 1877 |
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Edizione |
[Ed. stereotipa, 8. ristampa] |
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Descrizione fisica |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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3. |
Record Nr. |
UNINA9910789582803321 |
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Titolo |
Advances in biotechnology . Volume IV Current developments in yeast research : proceedings of the Fifth International Yeast Symposium held in London, Canada, July 20-25, 1980 / / edited by Graham G. Stewart and Ingre Russell ; general editor, Muray Moo-Young |
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Pubbl/distr/stampa |
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Ontario, Canada : , : Pergamon Press, , 1981 |
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©1981 |
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ISBN |
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Descrizione fisica |
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1 online resource (699 p.) |
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Collana |
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Advances in Biotechnology ; ; Volume IV |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and indexes. |
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Nota di contenuto |
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Front Cover; Advances in Biotechnology; Copyright Page; Editorial Board; Table of Contents; Preface; Section I:Industrial and Agricultural Uses; CHAPTER 1. YEAST - ALCOHOL PRODUCTION AND BREAD MAKING; ABSTRACT; KEYWORDS; FUEL ALCOHOL; BEVERAGES; BAKING; REFERENCES; CHAPTER 2. REGULATORY FACTORS IN ALCOHOL FERMENTATIONS; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; REFERENCES; CHAPTER 3. THE GENETIC MANIPULATION OF INDUSTRIAL YEAST STRAINS; ABSTRACT; KEYWORDS; INTRODUCTION; HYBRIDIZATION; FUSION; TRANSFORMATION; ACKNOWLEDGEMENT; REFERENCES |
CHAPTER 4. OPTIMIZATION OF YEAST PRODUCTION FROM EFFLUENTS USING FLOCCULENT STRAINSABSTRACT; KEYWORDS; MATHEMATICS; BIOLOGICAL PRE-REQUISITES FOR LONG TERM OPERATION; CONDITIONS FOR PRACTICAL OPERATION IN EFFLUENT TREATMENT; LOAD OPTIMIZATION; REFERENCES; ABBREVIATIONS AND SYMBOLS; CHAPTER 5. FLOCCULATION AND STARCH UTILIZATION IN SOME ANTIBIOTIC-RESISTANT MITOCHONDRIAL MUTANTS OF SACCHAROMYCES DIASTATICUS; ABSTRACT; KEYWORDS; INTRODUCTION; METHODS; RESULTS; DISCUSSION; LITERATURE CITED; CHAPTER 6. DEVELOPMENT OF A SEQUENCING BATCH YEAST REACTOR SYSTEM FOR ASSIMILATION OF LOW pH WASTES |
ABSTRACTKEYWORDS; INTRODUCTION; EXPERIMENTAL; RESULTS AND DISCUSSION; REFERENCES; CHAPTER 7. CELLULAR MATERIAL AND WATER POOLS IN BAKER'S YEAST DURING STORAGE; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS; REFERENCES; CHAPTER 8. THE INFLUENCE OF TEMPERATURE AND AVAILABILITY OF OXYGEN ON THE CARBOHYDRATES OF STORED BAKER'S YEAST; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS; DISCUSSION; REFERENCES; CHAPTER 9. THE DEVELOPMENT OF SPECIALISED YEAST STRAINS FOR USE IN SCOTCH MALT WHISKY FERMENTATIONS; ABSTRACT; KEYWORDS; INTRODUCTION |
DESIRABLE YEAST STRAIN PROPERTIESFERMENTATION PHYSIOLOGY; YEAST STRAIN DEVELOPMENT; ACKNOWLEDGDEMENT; REFERENCES; CHAPTER 10. PHYSIOLOGICAL CONTROL OF HIGHER ALCOHOL FORMATION IN THE SCOTCH WHISKY FERMENTATION; ABSTRACT; KEYWORDS; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; FINAL DISCUSSION AND CONCLUSIONS; REFERENCES; CHAPTER 11.STRUCTURE OF THE MICROBODY CRYSTALLOID IN METHANOL GROWN YEASTS AS A COMPOSITE CRYSTAL OF CATALASE AND ALCOHOL OXIDASE; ABSTRACT; KEYWORDS; INTRODUCTION; CUBIC LATTICE STRUCTURE; COMPOSITE CRYSTAL OF TWO ENZYMES; ENZYME ACTIVITIES; DISCUSSION |
REFERENCESCHAPTER 12. DEVELOPMENT OF NEW TECHNIQUES FOR THE GENETIC MANIPULATION OF BREWING YEASTS; ABSTRACT; KEYWORDS; REFERENCES; CHAPTER 13. PENTOSE FERMENTATION BY YEASTS; ABSTRACT; KEYWORDS; INTRODUCTION; RESULTS; DISCUSSION; REFERENCES; CHAPTER 14. APPLICATIONS DE L'ELECTROPHORESE DES FRACTIONS EXOCELLULAIRES DE LEVURES AU CONTROLE DE L'EFFICACITE D'UN LEVURAGE EN VINIFICATION; RESUME; KOTS CLES; INTRODUCTION; TECHNIQUE; APPLICATION AU CONTROLE DE L'EFFICACITE D'UN LEVURAGE EN VINIFICATION; REFERENCES |
CHAPTER 15 . CANDIDA CURVATA : UNE LEVURE INTERESSANTE POUR LA PRODUCTION DE PROTEINES A PARTIR DE LACTOSERUM |
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Sommario/riassunto |
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Advances in Biotechnology, Volume IV: Current Developments in Yeast Research covers the proceedings of the Fifth International Yeast Symposium. The book presents several papers that discuss several aspects of yeast. Comprised of 95 chapters and organized into eight |
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sections, the book first discusses the industrial and agricultural uses of yeast, and then covers genetics. The third section reviews sporulation and conjugation. Section IV tackles biochemistry, while Section V and Section VI talk about taxonomy, ecology, and cell cycle. The seventh section covers the Phaff symposium and the last s |
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