1.

Record Nr.

UNINA9910139948803321

Titolo

Obesity : science to practice / / [edited by] Gareth Williams, Gema Fruhbeck

Pubbl/distr/stampa

Chichester, West Sussex, UK ; ; Hoboken, NJ, : Wiley, 2008

ISBN

1-282-23751-9

9786612237515

0-470-71222-8

0-470-71221-X

Descrizione fisica

1 online resource (605 p.)

Altri autori (Persone)

WilliamsGareth, MD.

FruhbeckGema

Disciplina

616.85/26

Soggetti

Obesity

Metabolism - Disorders

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Obesity: Science to Practice; Contents; Preface; Contributors; 1 History of Obesity; Early human history; History of the biology of obesity; Descriptions and measurements of obesity; Metabolism and energy balance; Health hazards of obesity; Causes of obesity; Treatment of obesity; Growth of the scientifi c community; References; 2 Epidemiology and Social Impact of Obesity; Definitions of obesity; Current and recent prevalences of obesity; Childhood obesity; Predicted increases in obesity in adults; Comorbidities of obesity; Costs of obesity to society; Conclusions; References

3 Key Methodologies in Obesity Research and PracticeAnthropometric indices; Measurements of body composition; Measurements of fat distribution; Measuring energy balance; Assessing insulin sensitivity; References; 4 Adipose Tissue: Development, Anatomy and Functions; Introduction; Development of white adipose tissue; Structure of white adipose tissue; Fat storage and mobilization; Adipokines; Receptors expressed by adipose tissue; Brown adipose tissue; Adipose tissue development and dynamics; References; 5 The Regulation of Energy Balance: An Overview; Regulation of body fat and composition



Regulation of energy intake and expenditureLessons from other species: informative or misleading?; Causes of obesity; References; 6 Control of Eating; Flavour and orosensory signals; Gut signals; Metabolic signals; Adiposity signals; The neuroanatomy of eating regulation; The neuropharmacology of eating control; Modulating factors; References; 7 Energy Balance in Humans; Energy balance; Energy intake; Energy expenditure; Altered sympathetic activity in obesity; Substrate oxidation and predisposition to obesity; References; 8 Aetiology of Human Obesity; Lifestyle-related obesity

Changes in the prevalence of obesity over timeDrug-induced obesity; Endocrine causes of obesity; Specific genetic disorders; References; 9 Health Hazards of Obesity: An Overview; Measures of obesity as predictors of morbidity and mortality; Obesity and premature mortality; Cardiovascular disease; Type 2 diabetes; Malignancy; Gall-bladder disease; Osteoarthritis; Chronic renal failure; Ethnic differences in obesity-related predictors of disease; Conclusions; References; 10 Metabolic Complications of Obesity; Type 2 diabetes; The metabolic syndrome; Obesity and insulin resistance

Obesity and the development of type 2 diabetesDyslipidaemia in obesity and the metabolic syndrome; References; 11 Liver Disease in Obesity; Epidemiology; Pathogenesis of NAFLD in obesity; Pathology of NAFLD; Natural history of NAFLD; Clinical presentation; Investigation of suspected NAFLD; Management of patients with NAFLD; References; 12 Cardiovascular Disease and Obesity; General links between obesity and cardiovascular disease; Impact of obesity on the heart; Obesity and hypertension; Obesity and congestive heart failure; Obesity and coronary artery disease; Obesity and arrhythmias

Cardiac-associated adipose tissue

Sommario/riassunto

This comprehensive textbook addresses one of the major public health concerns of our era - obesity. Clearly and simply, Obesity: science to practice provides a balanced, coherent account of obesity: how to define and measure it, its epidemiology, the physiological basis, associated diseases, how to assess, manage and treat it, and also strategies for prevention. The book is generously illustrated, including graphs and flow charts for easy reference. The chapters cite key references so that interested readers may pursue a given topic in more detail. Well presented and thoroughly e