1.

Record Nr.

UNINA9910139946903321

Autore

Permi͡akov E. A (Evgeniĭ Anatolʹevich)

Titolo

Metalloproteomics [[electronic resource] /] / Eugene A. Permyakov

Pubbl/distr/stampa

Hoboken, N.J., : John Wiley & Sons, c2009

ISBN

1-282-27983-1

9786612279836

0-470-44775-3

0-470-44774-5

Descrizione fisica

1 online resource (820 p.)

Collana

Wiley series in protein and peptide science

Disciplina

572

572.6

Soggetti

Metalloproteins

Proteomics

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. 643-764) and index.

Nota di contenuto

The complexes of metal cations with low-molecular-mass compounds and of metal cations and proteins -- General regularities of the binding of metal cations to proteins -- Experimental methods used for studies of the binding of metal cations -- Calcium, calcium-binding proteins, and their major families -- Interactions of calcium-binding proteins with low-molecular-mass compounds, peptides, proteins, and membranes -- Calcium-binding proteins in various systems -- The binding of magnesium ions to proteins -- The binding of zinc ions to proteins -- The binding of copper ions to proteins -- Iron-binding proteins -- Molybdenum-containing and tungsten-containing proteins -- Proteins containing nickel and cobalt -- Manganese-containing proteins -- Sodium-binding and potassium-binding proteins -- Interactions of metal cations with nucleic acids -- "Non-physiological" metals.

Sommario/riassunto

Synthesizes the current knowledge in the field and provides new insights into medical applications Metalloproteomics is the large-scale study of metal-binding proteins. These proteins, which represent about one quarter of all the proteins in the Protein Data Bank, play important



roles in all biological systems and all biological processes. Metalloproteomics provides the latest information on all major families of metal-binding proteins, including their structural, physico-chemical, and functional properties, enabling readers to better understand these proteins. Moreover, the book demo