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Record Nr. |
UNINA9910139792203321 |
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Titolo |
Peripheral receptor targets for analgesia : novel approaches to pain treatment / / edited by Brian E. Cairns |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, c2009 |
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ISBN |
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1-282-29112-2 |
9786612291128 |
0-470-52222-4 |
0-470-52221-6 |
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Descrizione fisica |
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1 online resource (566 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Nociceptors |
Nerves, Peripheral |
Analgesia |
Analgesics |
Pain |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di contenuto |
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PERIPHERAL RECEPTOR TARGETS FOR ANALGESIA; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; PART I PERIPHERAL MECHANISM IN CLINICAL PAIN CONDITIONS; 1. Role of Peripheral Mechanisms in Craniofacial Pain Conditions; 2. Role of Peripheral Mechanisms in Spinal Pain Conditions; PART II SPECIFIC RECEPTOR TARGETS FOR PERIPHERAL ANALGESICS; 3. Voltage-Gated Sodium Channels in Peripheral Nociceptive Neurons as Targets for the Treatment of Pain; 4. Potassium Channels; 5. Voltage-Gated Calcium Channels as Targets for the Treatment of Chronic Pain; 6. Adenosine Receptors; 7. Acid-Sensing Ion Channels and Pain |
8. Vanilloid (TRPV1) and Other Transient Receptor Potential Channels9. Glutamate Receptors; 10. Serotonin Receptors; 11. Adrenergic Receptors; 12. Cholinergic Receptors and Botulinum Toxin; 13. Cannabinoids and Pain Control in the Periphery; 14. Opioid Receptors; 15. Calcitonin Gene-Related Peptide and Substance P; 16. Role of |
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Somatostatin and Somatostatin Receptors in Pain; 17. Cytokines (Tumor Necrosis Factor, Interleukins) and Prostaglandins; 18. Neurotrophic Factors and Pain; PART III DELIVERY SYSTEMS; 19. Topical and Systemic Drug Delivery Systems for Targeted Therapy |
20. Gene Therapy for Pain21. Topical Analgesics; Index |
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Sommario/riassunto |
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A unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain. A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a bo |
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