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Record Nr. |
UNINA9910815363403321 |
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Autore |
Hönig Florian |
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Titolo |
Automatic assessment of prosody in second language learning / / Florian Hönig |
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Pubbl/distr/stampa |
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Berlin : , : Logos Verlag, , [2017] |
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©2017 |
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ISBN |
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Descrizione fisica |
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1 online resource (264 pages) |
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Collana |
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Studien zur Mustererkennung |
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Disciplina |
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Soggetti |
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Second language acquisition - Ability. testing |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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PublicationDate: 20171123 |
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Sommario/riassunto |
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Long description: Worldwide there is a universal need for second language language learning. It is obvious that the computer can be a great help for this, especially when equipped with methods for automatically assessing the learner's pronunciation. While assessment of segmental pronunciation quality (i. ,e. whether phones and words are pronounced correctly or not) is already available in commercial software packages, prosody (i.e. rhythm, word accent, etc.) is largely ignored---although it highly impacts intelligibility and listening effort. The present thesis contributes to closing this gap by developing and analyzing methods for automatically assessing the prosody of non-native speakers. We study the detection of word accent errors and the general assessment of the appropriateness of a speaker's rhythm. We propose a flexible, generic approach that is (a) very successful on these tasks, (b) competitive to other state-of-the-art result, and at the same time (c) flexible and easily adapted to new tasks. |
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2. |
Record Nr. |
UNINA9910139751303321 |
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Autore |
Masella Roberta |
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Titolo |
Glutathione and sulfur amino acids in human health and disease / / Roberta Masella and Giuseppe Mazza |
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Pubbl/distr/stampa |
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ISBN |
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9786612278525 |
9781282278523 |
1282278525 |
9780470475973 |
0470475978 |
9780470475966 |
047047596X |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (626 p.) |
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Altri autori (Persone) |
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Disciplina |
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612.015756 |
612.3/98 |
612.398 |
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Soggetti |
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Glutathione - Psychological aspects |
Sulfur amino acids - Psychological aspects |
Glutathione - Therapeutic use |
Sulfur amino acids - Therapeutic use |
Glutathione - Metabolism |
Sulfur amino acids - Metabolism |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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GLUTATHIONE AND SULFUR AMINO ACIDS IN HUMAN HEALTH AND DISEASE; CONTENTS; PREFACE; CONTRIBUTORS; I INTRODUCTION; 1 GLUTATHIONE AND THE SULFUR-CONTAINING AMINO ACIDS: AN OVERVIEW; 1.1 Introduction; 1.2 Why Sulfur-Containing Amino Acids?; 1.3 S-Adenosylmethionine, Nature's Wonder Cofactor; 1.4 Glutathione; 1.5 Taurine-the Second Essential Sulfur-Containing Amino Acid?; 1.6 Conclusions; Acknowledgments; References; II CHEMISTRY AND METABOLISM OF GSH AND SULFUR AMINO ACIDS; 2 SULFUR AMINO ACIDS CONTENTS OF DIETARY PROTEINS: DAILY INTAKE AND |
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REQUIREMENTS; 2.1 Introduction |
2.2 Sulfur Amino Acids (SAA) Content of Dietary Protein2.3 Sulfur Amino Acid Intake; 2.4 Nutritional Requirement for Total Sulfur Amino Acids; 2.5 Conclusions; References; 3 CELLULAR COMPARTMENTALIZATION OF GLUTATHIONE; 3.1 Introduction; 3.2 Glutathione Content in Cells; References; 4 INTESTINAL METABOLISM OF SULFUR AMINO ACIDS; 4.1 Introduction; 4.2 Isotopic Approaches to Study Metabolism; 4.3 Evidence of Gut Sulfur Amino Acid Metabolism; 4.4 Other Key Players in Intestinal Sulfur Amino Acid Metabolism; 4.5 Cysteine in Redox Function and Oxidant Stress in the Gut |
4.6 Pathophysiology of Sulfur Amino Acid Metabolism in the GIT4.7 Conclusions; References; 5 HEPATIC SULFUR AMINO ACID METABOLISM; 5.1 Introduction; 5.2 Dietary Relation between Methionine and Cysteine; 5.3 Metabolic Relation between Hepatic Sulfur Amino Acids, B Vitamins, and Methyl Group Metabolism; 5.4 Regulation of Sulfur Amino Acid Metabolism and Related Metabolic Pathways in the Liver; 5.5 Impact of Physiologic and Nutritional Factors on Sulfur Amino Acid Metabolism; 5.6 Conclusions; References; III ANTIOXIDANT AND DETOXIFICATION ACTIVITIES |
6 GLUTATHIONE AND SULFUR CONTAINING AMINO ACIDS: ANTIOXIDANT AND CONJUGATION ACTIVITIES6.1 Introduction; 6.2 Reactive Oxygen Species and Antioxidants; 6.3 Glutathione Redox Cycle; 6.4 Regulation of GSH and Cysteine Levels; 6.5 Biotransformation; 6.6 ROS-Mediated Cellular Signaling; 6.7 Transcription Regulation of Antioxidant and Conjugation Enzymes; 6.8 Oxidative Stress and Diseases; References; 7 GLUTAREDOXIN AND THIOREDOXIN ENZYME SYSTEMS: CATALYTIC MECHANISMS AND PHYSIOLOGICAL FUNCTIONS; 7.1 Introduction; 7.2 General Characteristics of Glutaredoxins |
7.3 General Characteristics of Thioredoxins7.4 Glutaredoxin Mechanism of Action; 7.5 Thioredoxin Mechanism of Action; 7.6 Control of Grx Expression; 7.7 Control of Trx Expression in Mammalian Systems; 7.8 Cellular Functions of Grx; 7.9 Cellular Functions of Trx; 7.10 Reversible Sulfhydryl Oxidation and Disease; 7.11 Conclusions; References; 8 METHIONINE SULFOXIDE REDUCTASES: A PROTECTIVE SYSTEM AGAINST OXIDATIVE DAMAGE; 8.1 Introduction; 8.2 History of the Msr System; 8.3 MsrA and MsrB Protein Structure and Mechanism of Action; 8.4 Msr Reducing Requirement; 8.5 Other Members of the Msr Family |
8.6 The Msr System: Both a Repair Enzyme and a Scavenger of ROS |
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Sommario/riassunto |
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The complex roles of glutathione and sulfur amino acids in human health Glutathione (?-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease |
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