|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910139690003321 |
|
|
Titolo |
Therapeutic proteins [[electronic resource] ] : strategies to modulate their plasma half-lives / / edited by Roland Kontermann |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Weinheim, Germany, : Wiley-Blackwell, 2012 |
|
|
|
|
|
|
|
ISBN |
|
3-527-64478-4 |
1-283-45422-X |
9786613454225 |
3-527-64482-2 |
3-527-64479-2 |
|
|
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (374 p.) |
|
|
|
|
|
|
Altri autori (Persone) |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Protein drugs - Design |
Proteins - Therapeutic use |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references and index. |
|
|
|
|
|
|
Nota di contenuto |
|
pt. 1. General information -- pt. 2. Half-life extension through chemical and post-translational modifications -- pt. 3. Half-life modulation involving recycling by the neonatal Fc receptor -- pt. 4. Half-life extension with pharmaceutical formulations. |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals. |
|
|
|
|
|
|
|