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Record Nr. |
UNINA9910139612003321 |
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Titolo |
Protein chaperones and protection from neurodegenerative diseases / / edited by Stephan Witt |
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Pubbl/distr/stampa |
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Hoboken, : John Wiley & Sons, c2011 |
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ISBN |
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1-283-25775-0 |
9786613257758 |
1-118-06389-9 |
1-118-06390-2 |
1-118-06388-0 |
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Descrizione fisica |
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1 online resource (448 p.) |
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Collana |
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Wiley series on protein and peptide science |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Molecular chaperones |
Nervous system - Degeneration |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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PROTEIN CHAPERONES AND PROTECTION FROM NEURODEGENERATIVE DISEASES; CONTENTS; Preface; Introduction; Contributors; 1 Intrinsically Disordered Chaperones and Neurodegeneration; 2 Redox Regulation of Protein Misfolding, Synaptic Damage, and Neuronal Loss in Neurodegenerative Diseases; 3 Chaperone-Mediated Autophagy and Parkinson's Disease; 4 Chaperone and Anti-Chaperone Properties of Synuclein: Implications for Development, Aging, and Neurodegenerative Disease; 5 The Ubiquitin-Proteasome System in Neurodegenerative Diseases: More than the Usual Suspects |
6 Regulation of the Polyglutamine Androgen Receptor by the Hsp90/Hsp70-Based Chaperone Machinery7 Amyloid Remodeling by Hsp104; 8 Chaperone-Dependent Amyloid Assembly and Prion Toxicity; 9 Modulation of Amyloid Propagation in Yeast by Hsp70 and its Regulators and Chaperone Partners; 10 ALS and the Copper Chaperone CCS; 11 Emerging Area: TorsinA, a Novel ATP-Dependent Factor Linked to Dystonia; 12 Therapeutics: Harnessing the Power of Molecular and Pharmacological Chaperones; Index |
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Sommario/riassunto |
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How protein chaperones protect cells from neurodegenerative diseases |
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