1.

Record Nr.

UNINA9910139493503321

Titolo

Enzybiotics [[electronic resource] ] : antibiotic enzymes as drugs and therapeutics / / edited by Tomas G. Villa, Patricia Veiga Crespo

Pubbl/distr/stampa

Hoboken, NJ, : John Wiley & Sons, c2010

ISBN

1-282-68479-5

9786612684791

0-470-57054-7

0-470-57053-9

Descrizione fisica

1 online resource (296 p.)

Altri autori (Persone)

González VillaTomás

Veiga-CrespoPatricia

Disciplina

615.329

615.35

Soggetti

Enzymes - Therapeutic use

Antibacterial agents

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

ENZYBIOTICS; CONTENTS; PREFACE; CONTRIBUTORS; 1 ENZYBIOTICS AND THEIR POTENTIAL APPLICATIONS IN MEDICINE; 2 ADVANTAGES AND DISADVANTAGES IN THE USE OF ANTIBIOTICS OR PHAGES AS THERAPEUTIC AGENTS; 3 ENZYBIOTICS AS SELECTIVE KILLERS OF TARGET BACTERIA; 4 PHYLOGENY OF ENZYBIOTICS; 5 BACTERIOPHAGE LYSINS: THE ULTIMATE ENZYBIOTIC; 6 BACTERIOPHAGE HOLINS AND THEIR MEMBRANE-DISRUPTING ACTIVITY; 7 ANTI-STAPHYLOCOCCAL LYTIC ENZYMES; 8 MEMBRANE-TARGETED ENZYBIOTICS; 9 DESIGN OF PHAGE COCKTAILS FOR THERAPY FROM A HOST RANGE POINT OF VIEW; 10 IDENTIFYING PHAGE LYTIC ENZYMES: PAST, PRESENT, AND FUTURE

11 USE OF GENETICALLY MODIFIED PHAGES TO DELIVER SUICIDAL GENES TO TARGET BACTERIACONCLUDING REMARKS: THE FUTURE OF ENZYBIOTICS; INDEX

Sommario/riassunto

Presents the latest research and applications for a new, promising approach to fighting infectious diseases  Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry,



microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications. The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book e