1.

Record Nr.

UNINA9910139435003321

Titolo

Radical and radical ion reactivity in nucleic acid chemistry / / edited by Marc M. Greenberg

Pubbl/distr/stampa

Hoboken, New Jersey : , : Wiley, , [2009]

©2009

ISBN

0-470-52627-0

0-470-52626-2

Descrizione fisica

1 online resource (481 pages) : illustrations (some color)

Collana

Wiley series of reactive intermediates in chemistry and biology

Disciplina

572/.33

Soggetti

Nucleic acids - Effect of radiation on

DNA

Ionization

Free radicals (Chemistry)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Theoretical modeling of radiation-induced DNA damage / Anil Kumar and Michael D. Sevilla -- Radical reaction pathways initiated by direct energy deposition in DNA by ionizing radiation / William A. Bernhard -- Chemical reactions of the radical cations of nucleobases in isolated and cellular DNA : formation of single-base lesions / Jean Cadet ... [et al.] -- Reactivity of nucleic acid sugar radicals / Chryssostomos Chatgilialoglu -- Pyrimidine nucleobase radical reactivity / Marc M. Greenberg -- Reactivity of 5-halopyrimidines in nucleic acids / Ryn Tashiro and Hiroshi Sugiyama -- Kinetics of long-range oxidative electron transfer through DNA / Kiyohiko Kawai and Tetsuro Majima -- Radical intermediates during reductive electron transfer through DNA / Reji Varghese and Hans-Achim Wagenknecht -- Low-energy electron interaction with DNA : bond dissociation and formation of transient anions, radicals, and radical anions / Léon Sanche -- Electronic-affinic radiosensitizers / Peter Wardman -- Reactions of reactive nitrogen species and carbonate radical anions with DNA / Vladimir Shafirovich, Conor Crean, and Nicholas E. Geacintov -- Principles and applications of electrochemical oxidation of nucleic acids / H. Holden Throp and



Julie M. Sullivan -- DNA damage due to diradical-generating cyclizations / Sean M. Kerwin -- DNA damage by phenoxyl radicals / Richard A. Manderville.