1.

Record Nr.

UNINA9910139046103321

Titolo

Trypanosomatid diseases [[electronic resource] ] : molecular routes to drug discovery / / edited by Timo Jäger, Oliver Koch, and Leopold Flohé

Pubbl/distr/stampa

Weinheim, : Wiley-VCH, 2013

ISBN

3-527-67040-8

3-527-67038-6

1-299-40220-8

3-527-67039-4

Descrizione fisica

1 online resource (578 p.)

Collana

Drug discovery in infectious diseases ; ; v. 4

Altri autori (Persone)

JägerTimo

KochOliver

FlohéLeopold

Disciplina

616.936061

Soggetti

Parasitic diseases

Trypanosomatidae

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

pt. 1. Disease burden, current treatments, medical needs, and strategic approaches -- pt. 2. Metabolic peculiarities in the trypanosomatid family guiding drug discovery -- pt. 3. Validation and selection of drug targets in kinetoplasts -- pt. 4. Examples of target-based approaches and compounds under consideration.

Sommario/riassunto

This is the first resource to provide researchers in academia and industry with an urgently needed update summarizing the current knowledge and possibilities for drug intervention against Trypanosomatides all in one volume. As such, it covers every aspect of the topic from basic research findings, via current treatments to translational approaches in drug development and includes both human and livestock diseases. The outstanding editor and contributor team reads like a Who?s Who of the field, thus guaranteeing the outstanding quality of this ready reference.