1.

Record Nr.

UNINA9910138154503321

Autore

Sarantseva Svetlana

Titolo

Amyloidosis : mechanisms and prospects for therapy / / edited by Svetlana Sarantseva

Pubbl/distr/stampa

IntechOpen, 2011

Rijeka, Croatia : , : InTech, , [2011]

©2011

ISBN

953-51-6497-X

Descrizione fisica

1 online resource (228 pages)

Disciplina

616.3995

Soggetti

Amyloidosis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Amyloidoses are a heterogeneous group of diverse etiology diseases. They are characterized by an endogenous production of abnormal proteins called amyloid proteins, which are not hydrosoluble, form depots in various organs and tissue of animals and humans and cause dysfunctions. Despite many decades of research, the origin of the pathogenesis and the molecular determinants involved in amyloid diseases has remained elusive. At present, there is not an effective treatment to prevent protein misfolding in these amyloid diseases. The aim of this book is to present an overview of different aspects of amyloidoses from basic mechanisms and diagnosis to latest advancements in treatment.