1.

Record Nr.

UNINA9910137204903321

Autore

Jae Young Seong

Titolo

Neuropeptide GPCRs in neuroendocrinology / / topic editors Hubert Vaudry and Jae Young Seong

Pubbl/distr/stampa

Frontiers Media SA, 2014

[Lausanne, Switzerland] : , : Frontiers Media SA, , 2014

Descrizione fisica

1 online resource (825 pages) : illustrations; digital file(s)

Collana

Frontiers Research Topics

Frontiers in Endocrinology

Frontiers in Neuroscience

Soggetti

Neuroendocrinology

Neuropharmacology

Endocrinology

Animal Biochemistry

Human Anatomy & Physiology

Health & Biological Sciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references.

Sommario/riassunto

The human genome encompasses ≈ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic is to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that will illustrate the different facets of the studies currently conducted in this domain.