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1. |
Record Nr. |
UNINA9910137204403321 |
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Autore |
Jacqueline Kerr |
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Titolo |
Emerging technologies to promote and evaluate physical activity / / topic editors Dan J. Graham, James Aaron Hipp,Simon Marshall and Jacqueline Kerr |
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Pubbl/distr/stampa |
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Frontiers Media SA, 2014 |
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Switzerland : , : Frontiers Media SA, , 2014 |
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ISBN |
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Descrizione fisica |
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1 online resource (140 pages) : illustrations |
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Collana |
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Frontiers Research Topics |
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Disciplina |
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Soggetti |
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Physiology |
Human Anatomy & Physiology |
Health & Biological Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di bibliografia |
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Includes bibliographical references. |
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Sommario/riassunto |
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Increasingly, efforts to promote and measure physical activity are achieving greater precision, greater ease of use, and/or greater scope by incorporating emerging technologies. This is significant for physical activity promotion because more precise measurement will allow investigators to better understand where, when, and how physical activity is and is not occurring, thus enabling more effective targeting of particular behavior settings. Emerging technologies associated with the measurement and evaluation of physical activity are noteworthy because: (1) Their ease of use and transferability can greatly increase external validity of measures and findings; (2) Technologies can significantly increase the ability to analyze patterns; (3) They can improve the ongoing, systematic collection and analysis of public health surveillance due to real-time capabilities associated with many emerging technologies; (4) There is a need for research and papers about the cyberinfrastructure required to cope with big data (multiple streams, processing, aggregation, visualization, etc.); and (5) Increasingly blurred boundaries between measurement and intervention activity (e.g., the quantified-self /self-tracking movement) |
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may necessitate a reevaluation of the conventional scientific model for designing and evaluating these sorts of studies. |
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2. |
Record Nr. |
UNINA9910557371103321 |
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Autore |
Leone Marilisa |
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Titolo |
The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
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Descrizione fisica |
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1 online resource (230 p.) |
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Soggetti |
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Research & information: general |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological processes. The knowledge of the 3D structure of a protein, as well as the possible conformational transitions occurring upon interaction with diverse ligands, are essential to fully comprehend its biological function.In addition to globular, well-folded proteins, over the past few years, intrinsically disordered proteins (IDPs) have received a lot of attention. IDPs are usually aggregation-prone and may form toxic amyloid fibers and oligomers associated with several human pathologies. Peptides are smaller in size than proteins but similarly represent key elements of cells. A few peptides are able to work as tumor markers and find applications in the diagnostic and therapeutic fields. The conformational analysis of bioactive peptides is important to design novel potential drugs acting as selective modulators of specific receptors or enzymes. Nevertheless, synthetic peptides reproducing different protein fragments have frequently been implemented as model systems in folding studies relying on structural investigations in water and/or other environments.This book contains contributions |
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(seven original research articles and five reviews published in the journal Molecules) on the above-described topics and, in detail, it includes structural studies on globular folded proteins, IDPs and bioactive peptides. These works were conducted usingdifferent experimental methods. |
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