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1. |
Record Nr. |
UNINA9910449748803321 |
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Autore |
Jakobsen Janet R. <1960-> |
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Titolo |
Love the sin [[electronic resource] ] : sexual regulation and the limits of religious tolerance / / Janet R. Jakobsen and Ann Pellegrini |
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Pubbl/distr/stampa |
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New York, : New York University Press, c2003 |
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ISBN |
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0-8147-4325-0 |
1-4294-1440-5 |
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Descrizione fisica |
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1 online resource (189 p.) |
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Collana |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Homosexuality - Religious aspects - Christianity |
Gay rights - Religious aspects - Christianity |
Homosexuality - Government policy - United States |
Gay rights - United States |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Getting religion -- What's wrong with tolerance? -- Not born that way -- Free exercise of sex -- Valuing sex. |
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Sommario/riassunto |
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Sex. Religion. There is no denying that these two subjects are among the most provocative in American public life. Even the constitutional principle of church-state separation seems to give way when it comes to sex: the Supreme Court draws on theology as readily as it draws on case law when rendering decisions that touch on sexuality. In this compelling and carefully argued study, Janet R. Jakobsen and Ann Pellegrini examine this powerful and disturbing connection as they explore the reasons why secular institutions habitually use religion to regulate sexual life. From state legislatures to the halls of Congress and the Supreme Court, from daily newspapers to popular magazines and television talk shows, Jakobsen and Pellegrini illustrate the intensity of America's obsession with sex in the name of values and the dangers it poses to some of our most basic freedoms. Using a wide range of case studies, Love the Sin offers an insightful critique of the ways in which sexuality in general and homosexuality in particular are discussed and debated in the public arena. Additionally, the book sets forth constructive alternatives that highlight the vital links between sexual |
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and religious freedom and expose the hazards of using religion as a justification for regulating sexuality. A timely, necessary, and refreshing contribution to the many debates surrounding religion, morality, and sex, Love the Sin boldly dreams an America that lives up to its promise of freedom and justice for all. |
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2. |
Record Nr. |
UNINA9910137091503321 |
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Autore |
Christian Frezza |
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Titolo |
The metabolic challenges of immune cells in health and disease |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (80 p.) |
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Collana |
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Frontiers Research Topics |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Obesity and its co-morbidities, including atherosclerosis, insulin resistance and diabetes, are a world-wide epidemic. Inflammatory immune responses in metabolic tissues have emerged as a universal feature of these metabolic disorders. While initial work highlighted the contribution of macrophages to tissue inflammation and insulin resistance, recent studies demonstrate that cells of the adaptive immune compartment, including T and B lymphocytes and dendritic cells also participate in obesity-induced pathogenesis of these conditions. However, the molecular and cellular pathways by which the innate and adaptive branches of immunity control tissue and systemic metabolism remain poorly understood. To engage in growth and activation, cells need to increase their biomass and replicate their genome. This process presents a substantial bioenergetic challenge: growing and activated cells must increase ATP production and acquire or synthesize raw materials, including lipids, proteins and nucleic acids. To do so, they actively reprogram their intracellular metabolism from catabolic mitochondrial oxidative phosphorylation to glycolysis and |
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other anabolic pathways. This metabolic reprogramming is under the control of specific signal transduction pathways whose underlying molecular mechanisms and relevance to physiology and disease are subject of considerable current interest and under intense study. Recent reports have elucidated the physiological role of metabolic reprogramming in macrophage and T cell activation and differentiation, B- and dendritic cell biology, as well as in the crosstalk of immune cells with endothelial and stem cells. It is also becoming increasingly evident that alterations of metabolic pathways play a major role in the pathogenesis of chronic inflammatory disorders. Due to the scientific distance between immunologists and experts in metabolism (e.g., clinicians and biochemists), however, there has been limited cross-talk between these communities. This collection of articles aims at promoting such cross-talk and accelerating discoveries in the emerging field of immunometabolism. |
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