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1. |
Record Nr. |
UNISA996397227003316 |
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Titolo |
The embassadour of peace [[electronic resource] ] : being a strange and wonderful relation of a white dove seated on a rain-bow. That appears to several persons, in the parish of Peter's Carlile; particularly to Mrs. Isabel Fletcher, (wife to Mr. Fletcher, apothecary.) To whom it relates strange and wonderful things, concerning the state of affairs in this nation; very positively asserting universal peace and plenty to all Christendom, the ensuing year 1697. Proving the subversion of the French king, from several texts of scripture; especially from the last verse of the 31st psalm. To which is added, its disputes with several ministers; as also its pious prayers and exhortations to all the people that dayly far and near flock to see it. The truth of all which, is confirm'd by the testimony of two letters, the one sent to the Reverend Dr. Simpson, and the other writ by the worshipful Justice Patrickson |
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Pubbl/distr/stampa |
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[Edinburgh, : Re-printed by the heirs and successors of Andrew Anderson ..., 1696] |
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Descrizione fisica |
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Soggetti |
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Visions - Great Britain - 17th century - Religious aspects |
Christian art and symbolism |
Oracles |
Doves in literature |
Birds - Religious aspects |
Great Britain History Prophecies Early works to 1800 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Caption title. |
Imprint from colophon. |
Reproduction of original in: National Library of Scotland. |
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Sommario/riassunto |
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2. |
Record Nr. |
UNINA9910136797203321 |
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Autore |
Matthew R. Roesch |
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Titolo |
Neural Circuitry of Behavioral Flexibility: Dopamine and Related Systems |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (165 p.) |
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Collana |
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Frontiers Research Topics |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Decades of research have identified a role for dopamine neurotransmission in prefrontal cortical function and flexible cognition. Abnormal dopamine neurotransmission underlies many cases of cognitive dysfunction. New techniques using optogenetics have allowed for ever more precise functional segregation of areas within the prefrontal cortex, which underlie separate cognitive functions. Learning theory predictions have provided a very useful framework for interpreting the neural activity of dopamine neurons, yet even dopamine neurons present a range of responses, from salience to prediction error signaling. The functions of areas like the Lateral Habenula have been recently described, and its role, presumed to be substantial, is largely unknown. Many other neural systems interact with the dopamine system, like cortical GABAergic interneurons, making it critical to understand those systems and their interactions with dopamine in order to fully appreciate dopamine's role in flexible behavior. Advances in human clinical research, like exome sequencing, are driving experimental hypotheses which will lead to fruitful new research directions, but how do (or should?) these clinical findings inform basic research? Following new information from these techniques, we may begin to develop a fresh understanding of human disease states which will inform novel treatment possibilities. However, we need an operational framework with which to interpret these new findings. Therefore, the purpose of this Research Topic is to integrate |
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what we know of dopamine, the prefrontal cortex and flexible behavior into a clear framework, which will illuminate clear, testable directions for future research. |
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