1.

Record Nr.

UNINA9910136529303321

Titolo

Gastrointestinal neoplasia / / editors, Paul J. Limburg, Dan A. Dixon ; consulting editor, Gary W. Falk

Pubbl/distr/stampa

Philadelphia, Pennsylvania : , : Elsevier, , 2016

©2016

ISBN

0-323-46278-2

Descrizione fisica

1 online resource (228 p.)

Collana

Gastroenterology Clinics of North America, , 0889-8553 ; ; Volume 45, Number 3

Disciplina

616.3307545

Soggetti

Endoscopy

Endoscopes

Gastroenterology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

"Clinics Review Articles"--Cover.

Nota di contenuto

Title page; Table of Contents; Copyright; Contributors; Forthcoming Issues; Preface; Esophageal Cancer; Key points; Introduction; Squamous cell carcinoma of the esophagus; Adenocarcinoma of the esophagus; Barrett's esophagus; Diagnosis; Staging; Treatment; The future of diagnosis and management; Other esophageal malignancies; Summary; Supplementary data; Current Perspectives on Gastric Cancer; Key points; Global impact of gastric cancer; Gastric cancer causes and risk factors; Gastric cancer classification; Gastric cancer prevention; Screening and surveillance; Diagnostic evaluation

Clinical managementPrognosis and survivorship; Pancreatic Cancer: A Review; Key points; Introduction and public health concerns; Molecular pathways/genetics; Risk factors; Early detection; Diagnostic evaluation; Clinical management; Surgery; Chemotherapy; Survivorship; Future directions; Summary; Small Bowel Adenocarcinoma; Key points; Introduction; Epidemiology; Tumor phenotyping; Risk factors for small bowel adenocarcinoma; Diagnosis of small bowel adenocarcinoma; Prognosis; Treatment; Summary; Colorectal Cancer: Genetics is Changing Everything; Key points; Introduction; Molecular pathways



Public health burdenRisk and protective factors; Screening and early detection; Diagnostic evaluation; Prognosis; Clinical management; Survivorship; Knowns and Known Unknowns of Gastrointestinal Stromal Tumor Adjuvant Therapy; Key points; Introduction; Case series from the era before imatinib therapy; Selected trials of adjuvant imatinib; Z9000 (1-year imatinib); Z9001 (0 vs 1-year adjuvant imatinib); European Organisation for Research and Treatment of Cancer intergroup trial (0 vs 2-year adjuvant imatinib)

Scandinavian Sarcoma Group XVIII/Arbeitsgemeinschaft Internistische Onkologie (1- vs 3-year adjuvant imatinib)Ongoing adjuvant trials; Neoadjuvant therapy; Reimaging; Sensitivity of gastrointestinal stromal tumor-specific KIT and PDGFRA mutations to imatinib; National and international guidelines; Commentary; Neuroendocrine Tumors; Key points; Introduction; Clinical presentations of gastroenteropancreatic neuroendocrine tumors; Diagnostic modalities; Markers of neuroendocrine tumors disease; Management; Summary; Heritable Gastrointestinal Cancer Syndromes; Key points; Genes and cancer

Colorectal cancerColonic polyposis syndromes; Gastric cancer; Pancreatic adenocarcinoma; Clinical approach to genetic risk assessment for gastrointestinal cancer risk; Molecular Detection of Gastrointestinal Neoplasia: Innovations in Early Detection and Screening; Key points; Introduction; Mechanisms, media, and markers; A glimpse at emergent and experimental new molecular tools for gastrointestinal cancer screening; Summary; The Role of the Microbiome in Gastrointestinal Cancer; Key points; Introduction; Gastric cancer; Helicobacter pylori

Bacterial and host factors affecting the propensity toward gastric cancer