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1. |
Record Nr. |
UNINA9910135041903321 |
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Titolo |
Lysosomes : biology, diseases, and therapeutics / / edited by Frederick R. Maxfield, James M. Willard, Shuyan Lu |
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Pubbl/distr/stampa |
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Hoboken, New Jersey : , : Wiley, , 2016 |
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©2016 |
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ISBN |
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1-118-97831-5 |
1-118-97830-7 |
1-118-97832-3 |
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Descrizione fisica |
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1 online resource (562 p.) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Lysosomes an introduction / Frederick R. Maxfield -- Lysosome biogenesis and autophagy / Fulvio Reggiori, Judith Klumperman -- Multivesicular bodies: roles in intracellular and intercellular signalling / Emily R. Eden, Thomas Burgoyne, Clare E. Futter -- Lysosomes and mitophagy / Dominik Haddad, Patrik Verstreken -- Lysosome exocytosis and membrane repair / Rajesh K. Singh, Abigail S. Haka -- Role of lysosomes in lipid metabolism / Frederick R. Maxfield -- TFEB, master regulator of cellular clearance / Graciana Diez-Roux and Andrea Ballabio -- Lysosomal membrane permeabilization in cell death / Urska Repnik, Boris Turk -- The lysosome in aging-related neurodegenerative diseases / Ralph A. Nixon -- Lysosome and cancer / Marja Jaattela and Tuula Kallunki -- The genetics of sphingolipid hydrolases & sphingolipid storage diseases / Edward H. Schuchman and Calogera M. Simonaro -- Lysosome-related organelles : modifications of the lysosome paradigm / Adriana R. Mantegazza and Michael S. Marks -- Autophagy inhibition as a strategy for cancer therapy / Xiaohong Ma, Shengfu Piao, Quentin Mcafee, and Ravi K. Amaravadi -- Autophagy enhancers, are we there yet? / Shuyan Lu & Ralph A Nixon -- Pharmacological chaperones as potential therapeutics for lysosomal storage disorders: preclinical research to clinical studies / Robert E. |
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Boyd, Elfrida R. Benjamin, Su Xu, Richie Khanna, and Kenneth J. Valenzano -- Endosomal escape pathways for delivery of biologics / Philip L. Leopold -- Lysosomes and antibody drug conjugates / Michelle Mack, Jennifer Kahler, Boris Shor, Michael Ritchie, Maureen Dougher, Matthew Sung, and Puja Sapra -- The mechanisms and therapeutic consequences of amine-containing drug sequestration in lysosomes / Nadia Hamid and Jeffrey P. Krise -- Lysosome dysfunction : an emerging mechanism of xenobiotic-induced toxicity / Shuyan Lu, Bart Jessen, Yvonne Will & Greg Stevens -- Lysosomes and phospholipidosis in drug development and regulation / James M. Willard and Albert De Felice. |
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2. |
Record Nr. |
UNINA9910838362203321 |
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Autore |
Nieto Morales Concepción |
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Titolo |
Análisis y Valoración de la Prueba Pericial. Social, Educativa, Psicológica y Médica. el Perito Judicial [[electronic resource]] |
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Pubbl/distr/stampa |
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Madrid : , : Dykinson, S.L., , 2021 |
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©2021 |
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ISBN |
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Descrizione fisica |
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1 online resource (259 pages) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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3. |
Record Nr. |
UNINA9910960286803321 |
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Autore |
Krol Piotr |
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Titolo |
Linear polyurethanes : synthesis methods, chemical structures, properties and applications / / by Piotr Krol |
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Pubbl/distr/stampa |
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Leiden ; ; Boston, : VSP, 2008 |
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Leiden ; ; Boston : , : VSP, , 2008 |
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ISBN |
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1-04-019455-9 |
0-429-08840-X |
1-283-12665-6 |
9786613126658 |
90-04-18816-9 |
1-60119-611-3 |
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Descrizione fisica |
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1 online resource (271 p.) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p [241]-250) and index. |
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Nota di contenuto |
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Basic raw materials for the production of linear polyurethanes -- Reaction mechanisms occurring in the polyurethane production process -- General kinetic model for the diisocyanates and polyols polyaddition process -- Principal reactions utilised in the polyurethane technology -- Manufacturing methods for polyurethane elastomers -- Non-isocyanate methods for the synthesis of N-substituted linear polyurethanes -- Determination of molecular weights of linear polyurethanes by gelpermeation chromatography (GPC) and mass spectrometry (MS) methods -- Polyurethane ionomers -- Examples of copolymers with linear polyurethanes -- Microphase separation in polyurethane elastomers. Glass transition temperatures--analysis of phase structures by DSC, SAXS and AFM methods -- Intermolecular interactions free surface energy -- Thermal properties of linear polyurethanes -- Modern trends in property programming and in applications for linear polyurethanes. |
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Sommario/riassunto |
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This volume describes in detail the mechanisms of the diisocyanates and polyols polyaddition process as well as its kinetic and process |
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aspects important for obtaining linear polyurethanes. General kinetics of the process and its experimental verification, using GPC chromatography as well as NMR spectroscopy and MALDI-ToF spectrometry, are presented. Accompanied by over 400 references, the author presents synthesis methods, physicochemical properties of linear polyurethanes (analyzed with DCS, TG, DMTA, Rtg, AFM microscopy methods) as semiproducts for foams, elastomers, lacquers and coatings. |
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