Asymmetric Synthesis II [[electronic resource] ] : More Methods and Applications

• Record Nr.: UNINA9910133857603321
• Autore: Christmann Mathias
• Pubbl/distr/stampa: Weinheim, : Wiley, 2013
• ISBN: 3-527-65223-X; 3-527-65225-6; 1-299-47604-X; 3-527-65226-4
• Descrizione fisica: 1 online resource (432 p.)
• Altri autori (Persone): Br?seStefan
• Disciplina: 541.39
• Soggetti: Asymmetric synthesis; Chemistry; Physical Sciences & Mathematics; Organic Chemistry; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di contenuto: Asymmetric Synthesis; Contents; List of Contributors; 1 Catalytic Enantioselective Alkylation of Prochiral Ketone Enolates; Background; Strategy and Results; Asymmetric Allylic Alkylation in Total Synthesis; Conclusions; CV of Corey M. Reeves; CV of Brian M. Stoltz; References; 2 Point-to-Planar Chirality Transfer in Total Synthesis: Scalable and Programmable Synthesis of Haouamine A and Its Atropisomer; Introduction; Synthetic Strategy Featuring Point-to-Planar Chirality Transfer; Programmable Synthesis of Haouamine A and Its Atropisomer; CV of Noah Z. Burns; CV of Phil S. Baran; References; 3 Tethered AminohydroxylationIntroduction and Background; Tethered Aminohydroxylation; a) First Generation of Reoxidants; b) N-Sulfonyloxy Carbamates; c) Carbonyloxycarbamates as Reoxidants for Osmium; Amide-Based Reoxidants; Evidence for the Mechanism of the TA Reaction; Applications in Organic Synthesis; Conclusion and Future Work; CV of Timothy J. Donohoe; CV of Stefanie Mesch; References; 4 Organocatalyzed Transformations of a, b-Unsaturated Carbonyl ; Compounds through Iminium Ion Intermediates; CV of Nicholas C. O. Tomkinson; CV of Julian H. Rowley; References; 5 The Renaissance of Silicon-Stereogenic Silanes: A Personal AccountBackground; Results; a) Intermolecular Chirality Transfer from Silicon to Carbon: Diastereoselective Palladium(II)-Catalyzed C-Si Bond Formation; b) Silicon-Stereogenic Silane as Stereochemical Probe: B(C6F5)3-Catalyzed Carbonyl Reduction; c) Kinetic Resolution with Silicon-Stereogenic Silanes: Cu-H-Catalyzed Diastereoselective Si-O Coupling; Conclusion; CV of Martin Oestreich; CV of Andreas Weickgenannt; References; 6 Asymmetric Dienamine Activation; Introduction; Historic Background; Results; Conclusion; CV of Mathias ChristmannReferences; 7 Asymmetric Brønsted Acid Catalysis; Introduction and Background; Strategy; Results; Summary; CV of Iuliana Atodiresei; CV of Uxue Uria; CV of Magnus Rueping; References; 8 Quaternary Stereogenic Centers by Enantioselective b-Carbon Eliminations from tert-Cyclobutanols; Background; Objective: Enantioselective Formation of Quaternary Stereogenic Centers in Combination with Reactive Alkyl-Rhodium Intermediates; Selective Generation of the Alkyl-Rhodium Species and Its Downstream Reactivities; CV of Nicolai Cramer; CV of Tobias Seiser; References; 9 Total Synthesis of Oseltamivir and ABT-341 Using One-Pot TechnologyIntroduction; Results; a) Total Synthesis of (-)-Oseltamivir via Two One-Pot Processes; b) Total Synthesis of ABT-341 by One-Pot Sequence; Conclusions; CV of Yujiro Hayashi; CV of Hayato Ishikawa; References; 10 Enantioselective Annulations with Chiral N-Mesityl N-Heterocyclic Carbenes; Introduction; Catalytic Generation of Chiral Enolate Equivalents; Catalytic Generation of Homoenolate Equivalents; Enantioselective Cascade Reactions Catalyzed by Chiral N-Heterocyclic Carbenes; Catalytic Annulations via a, b-Unsaturated Acyl Azoliums
• Sommario/riassunto: Continuing the proven and successful concept of the well-received textbook ""Asymmetric Synthesis - The Essentials"", this is a brief and timely update on the latest developments in asymmetric synthesis and selected applications in natural product synthesis, chemical industry and materials science. As such, it covers a broad range of topics in all important areas, including metal catalysis, organocatalysis, physical organic chemistry, and analytical chemistry.Each contribution is similarly structured, while the short biographies of the experts are a useful tool for students selecting t