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Record Nr. |
UNINA9910139601103321 |
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Titolo |
Protein kinases as drug targets [[electronic resource] /] / edited by Bert Klebl, Gerhard Müller, and Michael Hamacher |
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Pubbl/distr/stampa |
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Weinheim, Germany, : Wiley-VCH, 2011 |
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ISBN |
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3-527-63349-9 |
1-283-28324-7 |
9786613283245 |
3-527-63347-2 |
3-527-63348-0 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (398 p.) |
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Collana |
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Methods and principles in medicinal chemistry ; ; v. 49 |
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Altri autori (Persone) |
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MüllerGerhard |
KleblBert |
HamacherMichael |
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Disciplina |
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Soggetti |
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Protein kinases |
Drugs - Design |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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pt. 1. Hit finding and profiling for protein kinases : assay development and screening, libraries -- pt. 2. Medicinal chemistry -- pt. 3. Application of kinase inhibitors to therapeutic indication areas. |
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Sommario/riassunto |
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This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on oncology drugs.Backed by recent clinical experience with first-generation drugs in the b |
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