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Record Nr. |
UNINA9910132241703321 |
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Autore |
Levy Gilberto |
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Titolo |
The biostatistics of aging : from Gompertzian mortality and to an index of aging-relatedness / / Gilberto Levy, Bruce Levin |
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Pubbl/distr/stampa |
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Hoboken, NJ : , : John Wiley & Sons Inc., , [2014] |
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©2014 |
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ISBN |
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1-118-64584-7 |
1-118-64567-7 |
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Descrizione fisica |
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1 online resource (270 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Aging - Statistical methods |
Mortality - Statistical methods |
Life spans (Biology) |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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THE BIOSTATISTICS OF AGING: From Gompertzian Mortality to an Index of Aging-Relatedness; Copyright; CONTENTS; PREFACE AND ACKNOWLEDGMENT; 1 Introduction; 2 An Account of Gompertzian Mortality through Statistical and Evolutionary Arguments; 2.1 The Statistical Theory of Extreme Values; 2.1.1 Background to Results; 2.1.2 Original Results; 2.2 The Evolutionary Theory of Aging; 2.2.1 The Argument for Gompertzian Mortality; 2.2.2 Boundaries of the Argument; 3 The Argument against Gompertzian Mortality; 3.1 Departures from the Gompertz Model; 3.2 An Evolution-Based Model of Causation |
4 The Index of Aging-Relatedness 4.1 A Survival Mixture Model of the Gompertz and Weibull Distributions; 4.2 Definition and Interpretation of the Index of Aging-Relatedness; 4.3 The Survival Mixture Model and Competing Risks; 4.4 Estimation of the Model Parameters; 4.5 Illustrative Application: The Israeli Ischemic Heart Disease Study; 4.6 Precision of Estimation; 5 Discussion: Implications; 5.1 The Meaning of the Gompertz Parameter; 5.2 Age as a Risk Factor for Disease; 5.3 Are Aging-Related Diseases an Integral Part of Aging?; 5.4 Biological versus Chronological Aging |
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