1.

Record Nr.

UNINA9910131544103321

Titolo

Clinical guide to transplantation in lymphoma / / edited by Bipin N. Savani, MD, Mohamad Mohty, MD, PhD

Pubbl/distr/stampa

Chichester, [England] : , : Wiley Blackwell, , 2015

©2015

ISBN

1-118-86327-5

1-118-86326-7

1-118-86328-3

Descrizione fisica

1 online resource (288 p.)

Disciplina

616.99446

Soggetti

Lymphomas - Surgery

Stem cells - Transplantation

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Title page; Copyright page; Contents; List of contributors; Foreword; Introduction; Declaration of commercial interest; References; Section 1 Transplantation in lymphomas; Chapter 1 Lymphoma and transplantation: historical perspective; Brief history of hematopoietic cell transplantation; History of autologous HCT in non-Hodgkin lymphoma; History of autologous HCT in Hodgkin lymphoma; History of allogeneic HCT in lymphoma; General historical considerations; References; Chapter 2 Lymphoma: working committee and data reporting after transplantation in lymphoma; Introduction; Registry structure

Working committees Data reporting; Overcoming challenges to data reporting; Flow of data; Data quality; The Lymphoma Working Committee; Statistical methods; Type of data; Intervals and patient selection; Unadjusted comparison; Adjusted comparison; Selected examples from the CIBMTR Lymphoma Committee; Value for young investigators; Value for public and other stakeholders; Conclusion; References; Chapter 3 Use of transplantation in lymphoma: adults; Introduction; Hodgkin lymphoma; Non-Hodgkin lymphoma; Diffuse large B-cell lymphoma; Follicular lymphoma; Histologic transformation



to DLBCL

Mantle cell lymphoma Burkitt lymphoma; Primary CNS lymphoma; Peripheral T-cell lymphoma; Prognostic tools; Maintenance therapies; Novel therapies; Conclusions; References; Chapter 4 Hematopoietic stem cell transplantation for lymphoma in children, adolescents, and young adults; Introduction; Principles of autologous and allogeneic HSCT in pediatric lymphomas; Hodgkin lymphoma; Lymphoblastic lymphoma; Anaplastic large-cell lymphoma; Mature B-cell lymphomas: Burkitt lymphoma, diffuse large B-cell lymphoma, and primary mediastinal B-cell lymphoma; Future directions; Conclusions; References

Chapter 5 Preparative regimens for lymphoma: autologous hematopoietic stem cell transplantation Rationale for chemotherapy dose intensification for disease eradication; Traditional preparative regimens; Incorporation of monoclonal antibodies in autologous HCT preparative regimens; Rituximab; Monoclonal antibodies conjugated to radionuclide; Novel agents used in preparative regimens; Future directions; References; Chapter 6 Preparative regimens for lymphoma: allogeneic hematopoietic stem cell transplantation; Introduction; Myeloablative conditioning regimens for lymphomas

Reduced-intensity conditioning regimens RIC allo-HCT in diffuse large B-cell lymphoma; RIC allo-HCT for follicular lymphoma; RIC allo-HCT in mantle cell lymphoma; RIC allo-HCT in Hodgkin lymphoma; Incorporating monoclonal antibodies in preparative regimens for allo-HCT; Alternative donor sources; Umbilical cord blood cells; Haploidentical transplantation; Vaccine strategies in allo-HCT; Discussion and future direction; References; Chapter 7 Pretransplantation evaluation, comorbidities, and nondisease-related eligibility criteria for transplantation in lymphoma; Introduction; Initial steps

Preparation for transplant center evaluation