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Record Nr. |
UNINA9910131531803321 |
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Autore |
Alex Alexander A. |
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Titolo |
Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / / edited by Alexander Alex, C. John Harris, Dennis A. Smith |
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Pubbl/distr/stampa |
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Hoboken, New Jersey : , : Wiley, , 2016 |
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©2016 |
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ISBN |
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1-118-91434-1 |
1-118-81958-6 |
1-118-81944-6 |
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Descrizione fisica |
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1 online resource (373 p.) |
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Disciplina |
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Soggetti |
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Pharmaceutical industry - Management |
Pharmaceutical industry - Capital productivity |
Industrial efficiency |
Drug development |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, |
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organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton. |
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