1.

Record Nr.

UNINA9910131339603321

Autore

Lednicer Daniel

Titolo

Antineoplastic drugs : organic synthesis / / Daniel Lednicer

Pubbl/distr/stampa

Chichester, England : , : Wiley, , 2015

©2015

ISBN

1-118-89256-9

1-118-89255-0

1-118-89257-7

Descrizione fisica

1 online resource (230 p.)

Classificazione

SCI007000

Disciplina

616.994061

Soggetti

Antineoplastic agents

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and indexes.

Nota di contenuto

Title Page; Copyright Page; Contents; Preface; Introduction; Chapter 1 Alkylating Agents; 1.1 bis-Chloroethyl Amines; 1.2 Several Other Chloroethyl Agents; 1.3 Platinum-Based Antineoplastic Agents; 1.4 Miscellaneous Alkylating Agents; References; Chapter 2 Antimetabolites; 2.1 Introduction; 2.2 Folate Antagonists; 2.2.1 Compounds with Glutamate Side Chain; 2.2.2 Compounds Lacking the Glutamate Moiety; 2.2.3 Methoxylated Benzenes; 2.3 Pyrimidines and Purines; 2.3.1 Aglycones; 2.3.2 Saccharide-Linked Compounds; References; Chapter 3 Hormone Blocking Anticancer Drugs; 3.1 Introduction

3.2 Estrogen Antagonists3.2.1 Estrogen Antagonists; 3.2.2 Aromatase Inhibitors; 3.3 Androgen Antagonists; 3.3.1 Non-steroidal Antian drogens; 3.3.2 Steroid Androgen Antagonists; References; Chapter 4 Topoisomerase Inhibitors; 4.1 Introduction; 4.2 Anthracyclines; 4.3 Anthraquinones and Anthrapyrazoles; 4.3.1 Anthraquinones with Two Aminoalkyl Side Chains; 4.3.2 Anthraquinones with a Fused Pyrazole Ring; 4.3.3 Heterocyclic Anthraquinones; 4.4 Camptothecins; 4.4.1 Compounds from Modified Camptothecin; 4.4.2 Camptothecins by Total Synthesis; 4.5 Miscellaneous Topoisomerase Inhibitors; References

Chapter 5 Mitotic Inhibitors5.1 Introduction; 5.2 Taxanes; 5.3 Wholly



Synthetic Compounds; 5.3.1 Carbocyclic Compounds; 5.3.2 Peptide-Like Inhibitors; 5.3.3 Monocyclic Heterocyclic Inhibitors; 5.3.4 Bicyclic 5:6 Heterocyclic Inhibitors; 5.3.5 Bicyclic 6:6 Heterocyclic Tubulin Inhibitors; References; Chapter 6 Matrix Metalloproteinase Inhibitors; 6.1 Introduction; 6.2 Hydroxamates; 6.2.1 Agents with an Isobutyl Moiety; 6.2.2 A Thiomorpholine; 6.2.3 Sulfamates; 6.2.4 Miscellaneous Compounds; References; Chapter 7 Histone Deacetylase Inhibitors; 7.1 Introduction; 7.2 Hydroxamates

7.3 PhenylenediaminesReferences; Chapter 8 Enzyme Inhibitor, Part I, Tyrosine Kinases; 8.1 Introduction; 8.2 Epidermal Growth Factor Inhibitors; 8.3 VEGF; 8.3.1 Fused Ring Compounds; 8.3.2 Linear Arrays; 8.4 SRC Nonreceptor Tyrosine Kinase; 8.5 PDGF; 8.6 EGF; 8.7 Other TKI; 8.7.1 Linear Arrays; 8.7.2 Compounds with Two Fused Rings; 8.8 Janus Kinase Inhibitors; References; Chapter 9 Enzyme Inhibitors: Part II Additional Targets; 9.1 Serine-Threonine Kinase Inhibitors; 9.2 Additional Enzyme Inhibitors; 9.2.1 Farnesyl Transferase Inhibitors; 9.2.2 Cyclin-Dependent Kinase Inhibitors

9.2.3 Proteasome Inhibitors9.2.4 PARP Inhibitors; 9.2.5 Various Other Enzyme Inhibitors; References; Chapter 10 Miscellaneous Antineoplastic Agents; 10.1 Acyclic; 10.2 Monocyclic; 10.3 Two Linked Rings; 10.4 Rings on a Chain; 10.4.1 Two Rings; 10.4.2 Four and More Rings; 10.5 Fused Rings; 10.5.1 Indoles; 10.5.2 Purine-Like; 10.5.3 Tetralins and a Naphthalene; 10.5.4 Etc.; References; Appendix A; Index of Heterocycle Syntheses; Subject Index; EULA

Sommario/riassunto

"Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations"--



2.

Record Nr.

UNINA9910340853203321

Autore

Fanchette Sylvie

Titolo

Discovering Craft Villages in Vietnam : Ten itineraries around Hà Nội / / Sylvie Fanchette, Nicholas Stedman

Pubbl/distr/stampa

Marseille, : IRD Éditions, 2018

ISBN

2-7099-2228-2

Descrizione fisica

1 online resource (326 p.)

Altri autori (Persone)

StedmanNicholas

DigregorioMichael

FanchetteSylvie

Soggetti

Asian Studies

Sociology & Anthropology

concurrence

village

industrialisation

Vietnam

activité sectorielle

secteur informel

division du travail

pollution des eaux continentales

sectorial activity

competition

division of work

pollution

informal sector

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

With their festivals and traditional industries, their commun halls, pagodas, temples, and vernacular buildings, the villages around Hà Nội possess a rich body of cultural, architectural and craft heritage. Less than one hour from the capital are over 500 specialist craft villages,



producing an array of religious or artistic objects, as well as food products, industrial goods, textiles, basketware and much more. Despite the trials and tribulations Vietnam has endured, these traditions have remained alive; today they consti­tute the basis of material, social and spiritual culture among the village communities of the Red River delta.  The artisans themselves, and their local institutions, see cultural tourism as a way of further improving the fortunes of the craft village communities and bringing their heritage to wider attention. Until recently, few guides or tourists had forayed into these settle­ments, some of which are lost in the maze of routes and tracks that criss-cross the rice paddies of the Hà Nội hinterland. The history and skills they harbour have been inaccessible to all but a few specialists. Few of the villages are signposted, yet between them they are home to three quarters of the architectural, religious and craft heritage of the upper delta.  This book, the fruit of several years' research by specialists working in northern Vietnam, comprises ten itineraries, blending potted histories, legends, descriptions of craft techniques, signposted walks and maps, designed to introduce travellers and lovers of Vietnamese culture to forty or so villages around Hà Nội. Many of us have seen their wares on sale in shops in and around the 36 streets of Hà Nội Old Quarter or in other cities in West. This book is about the true lives and enduring skills of the nameless artisans who made them.