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1. |
Record Nr. |
UNINA9910131100403321 |
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Titolo |
Castelli medievali e neomedievali in Emilia-Romagna : atti della giornata di studio, Bologna, 17 marzo 2005 / / a cura di Maria Giuseppina Muzzarelli, Antonella Campanini |
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Pubbl/distr/stampa |
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Descrizione fisica |
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Collana |
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DPM quaderni. Convegni ; ; 2 |
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Altri autori (Persone) |
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CampaniniAntonella |
MuzzarelliMaria Giuseppina |
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Disciplina |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di bibliografia |
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Includes bibliographical references. |
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2. |
Record Nr. |
UNINA9910298309403321 |
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Titolo |
Arrestins - Pharmacology and Therapeutic Potential / / edited by Vsevolod V. Gurevich |
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Pubbl/distr/stampa |
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
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ISBN |
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Edizione |
[1st ed. 2014.] |
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Descrizione fisica |
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1 online resource (441 p.) |
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Collana |
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Handbook of Experimental Pharmacology, , 0171-2004 ; ; 219 |
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Disciplina |
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Soggetti |
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Pharmacology |
Biochemistry |
Proteins |
Gene therapy |
Cell physiology |
Pharmacology/Toxicology |
Biochemistry, general |
Protein Structure |
Gene Therapy |
Cell Physiology |
Receptors |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Therapeutic Potential of Small Molecules and Engineered Proteins.-Arrestin Interactions with G Protein-coupled Receptors -- Arrestin-biased GPCR Agonists -- Arrestin-1 Expression Levels, Rod Function and Health -- Protective Functions of Arrestin-1 in Photoreceptors -- Arrestin-4 and Cone Function -- Enhanced Phosphorylation-independent Arrestins and Gene Therapy -- Targeting Particular Receptors with Redesigned Non-visual Arrestins.- Arrestins binding to clathrin, AP2 and Role in GPCR trafficking -- Arrestins in Ubiquitination and Deubiquitination -- Arrestin Self-association -- Arrestin-dependent Activation of ERK and Src -- Arrestin-dependent Activation of JNK Family Kinases -- Arrestin-Mediated P38 Activation.- Arrestin-dependent PDE Localization -- Arrestins in Cell Migration -- Arrestins |
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in Host-pathogen Interactions -- Arrestin Regulation of Small GTPases -- GPCRs and Arrestins in Airways: Implications for Asthma -- Arrestins as Regulatory Signaling Hubs in Cancer Pathways -- Arrestins in Pain and Anesthesia. |
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Sommario/riassunto |
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This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners. |
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