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1. |
Record Nr. |
UNISA996210377703316 |
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Titolo |
Microelectronics for Neural Networks and Fuzzy Systems, 5th International Conference On |
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Pubbl/distr/stampa |
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[Place of publication not identified], : IEEE Computer Society Press, 1996 |
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Disciplina |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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2. |
Record Nr. |
UNINA990009309150403321 |
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Autore |
Nunziata, Massimo <1924-> |
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Titolo |
L'opera di Le Corbusier : mostra itinerante a cura della Direzione degli affari culturali del Ministero degli esteri francese allestita dalla Sezione campana dell'IN/ARCH / relazione illustrativa svolta da Massimo Nunziata il 4 giugno 1966 nell'aula magna della Facoltà di ingegneria di Napoli |
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Pubbl/distr/stampa |
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Descrizione fisica |
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26 p., [12] c. di tav. : ill. ; 23 cm |
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Collana |
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Documenti IN/Arch. Sezione campana ; 1 |
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Disciplina |
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Locazione |
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Collocazione |
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FONDO ROSSI 5086 |
I(FN) A 75 |
I(FN) A 76 |
I(FN) A 77 |
P II 13 |
MTD 927 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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In testa al frontespizio: Istituto nazionale di architettura, Sezione campana |
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3. |
Record Nr. |
UNINA9910437808403321 |
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Titolo |
Characterization of protein therapeutics using mass spectrometry / / Guodong Chen, editor |
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Pubbl/distr/stampa |
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New York, : Springer, c2013 |
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ISBN |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (408 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Mass spectrometry |
Proteins - Therapeutic use |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions -- The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics -- Quantitative Analysis of Biologics Using Mass Spectrometry -- Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry -- Disulfide Linkages of an Albumin Fusion Protein -- Detailed Structural Characterization of Monoclonal Antibodies -- Application of Protein Mass Spectrometry in Impurity and Degradant Characterization -- Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting -- Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS -- Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry -- Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry. . |
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Sommario/riassunto |
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Protein therapeutics’ high efficacy, safety, and ability to treat life- |
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threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry. In Characterization of Protein Therapeutics using Mass Spectrometry, expert contributors from academia and industry highlight current approaches and future trends. The book discusses mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies and quantitative approaches. The book also covers various studies involving characterization of process related protein drug impurities/degradants, metabolites, PTMs and higher order structures of protein therapeutics. General practitioners in pharmaceutical research, specialists in analytical sciences, and graduate students studying mass spectrometry and pharmaceutical sciences will find this book useful because of the step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development. |
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