1.

Record Nr.

UNINA990001149860403321

Autore

Douglis, Avron

Titolo

A layering method for viscous, incompressible L/p flows occupying R/n / A. Douglis, E.B. Fabes

Pubbl/distr/stampa

Boston [etc.] : Pitman, 1984

Descrizione fisica

171 p. ; 25 cm

Collana

Research notes in mathematics ; 108

Altri autori (Persone)

Fabes, E. B.

Locazione

MA1

Collocazione

C-2-(108

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

2.

Record Nr.

UNINA9910523714603321

Titolo

Clinical applications of SPECT-CT / / edited by Hojjat Ahmadzadehfar, Hans-Jürgen Biersack, and Ken Herrmann

Pubbl/distr/stampa

Cham, Switzerland : , : Springer, , [2022]

©2022

ISBN

3-030-65850-3

Edizione

[Second edition.]

Descrizione fisica

1 online resource (316 pages)

Disciplina

616.07575

Soggetti

Single-photon emission computed tomography

Nuclear medicine

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Intro -- Contents -- 1: Physics and Technology of SPECT/CT -- 1.1  SPECT/CT: Combining Form with Function -- 1.2  The Development



of Multimodality SPECT/CT Imaging -- 1.3  Radiation and Interaction with Matter -- 1.3.1  Photon Attenuation -- 1.4  SPECT Instrumentation -- 1.4.1  Gamma Camera -- 1.4.2  Solid-State Detectors -- 1.5  SPECT Acquisition and Reconstruction -- 1.5.1  Projections and the Radon Transform -- 1.5.2  Image Reconstruction: Filtered Back-Projection (FBP) -- 1.5.3  Image Reconstruction: Iterative Techniques. -- 1.5.4  Corrections for Photon Attenuation and Scattering -- 1.5.5  Corrections for Resolution -- 1.6  CT for SPECT/CT -- 1.7  Quantitative SPECT/CT -- 1.8  Radiation Dose from SPECT/ CT -- 1.9  QC for SPECT/CT -- 1.10  Combined SPECT and CT -- References -- 2: SPECT Radiomics: The Current Landscape, Challenges, and Opportunities -- 2.1  Introduction -- 2.2  Radiomics as a Methodology -- 2.3  Clinical Application of Radiomics Using SPECT -- 2.3.1  Oncologic SPECT Radiomics -- 2.3.2  Neurologic SPECT Radiomics -- 2.3.3  Cardiac SPECT Radiomics -- 2.3.4  Other Applications of SPECT Radiomics -- 2.4  Challenges and Opportunities of SPECT Radiomics -- References -- 3: SPECT/CT for Dosimetry -- 3.1  Introduction -- 3.2  SPECT Versus Planar -- 3.3  SPECT/CT Versus SPECT -- 3.4  Choice of a Surrogate -- 3.5  SPECT/CT-Based Dosimetry Studies -- 3.5.1  Yttrium-90 Spheres Dose-Response -- 3.5.2  Yttrium-90 Spheres Dose-Toxicity -- 3.5.3  Yttrium-90 PRRT -- 3.5.4  Holmium-166 -- 3.5.5  Lutetium-177 Antibody -- 3.5.6  Lutetium-177 PRRT -- 3.5.7  Iodine-131 -- 3.5.8  Alpha Emitters -- 3.5.9  SPECT/CT-Based Individualized Therapy Planning -- 3.5.10  Perspectives: Compton Cameras -- 3.6  Conclusions -- References -- 4: SPECT/CT Imaging in Hyperparathyroidism and Benign Thyroid Disorders -- 4.1  Hyperparathyroidism -- 4.1.1  Embryology.

4.1.2  Pathophysiology, Treatment Goals, and Strategies -- 4.1.2.1  Primary Hyperparathyroidism -- 4.1.2.2  Secondary Hyperparathyroidism -- 4.1.2.3  Tertiary Hyperparathyroidism -- 4.1.3  Role of Parathyroid Scintigraphy -- 4.1.3.1  Primary Hyperparathyroidism -- Initial Surgery for pHPT -- Persistent or Recurrent HPT -- 4.1.3.2  Renal Hyperparathyroidism -- Initial Surgery for rHPT -- Persistent or Recurrent rHPT -- 4.1.4  Planar Parathyroid Scintigraphy -- 4.1.5  Dual-Phase Protocol -- 4.1.6  Subtraction Protocol -- 4.1.7  Sensitivity and Specificity -- 4.1.8  SPECT/CT -- 4.1.8.1  Primary Hyperparathyroidism -- 4.1.8.2  Renal Hyperparathyroidism -- 4.1.9  Conclusion Remarks -- 4.2  Benign Thyroid Disorders -- 4.2.1  Ectopic Thyroid Tissue -- 4.2.2  Intrathoracic Goitre -- 4.2.3  Ovarian Teratoma -- References -- 5: SPECT/CT for Thyroid Cancer Imaging -- 5.1  Introduction -- 5.2  Radioiodine SPECT/CT -- 5.3  Early Use of Radioiodine SPECT/CT -- 5.4  Utility of Post-therapy Radioiodine SPECT/CT -- 5.5  Utility of Diagnostic and Pre-ablation Radioiodine SPECT/ CT -- 5.6  SPECT/CT Evaluation of Unusual Radioactive Distributions -- 5.7  Changes to Clinical Management -- 5.8  Comparison to Other Imaging Modalities -- 5.9  Utility of Radioiodine SPECT/CT for Lesional Dosimetry -- 5.10  Disadvantages and Limitations of SPECT/CT -- 5.11  Conclusion -- References -- 6: SPECT/CT in Neuroendrocrine Tumours -- 6.1  Introduction -- 6.2  Epidemiology -- 6.3  Physiology -- 6.4  Somatostatin -- 6.4.1  Somatostatin Receptors -- 6.5  Classification -- 6.6  Diagnostical Tracers (Somatostatin Receptor-Based Imaging) -- 6.6.1  [111In]-DTPA-D-Phe1-Octreotide -- 6.6.2  [99mTc]-EDDA/HYNIC-Tyr3-Octreotide ([99mTc]-TEKTROTYD®) -- 6.6.3  [99mTc]-Depreotide (NeoSPECT®) -- 6.6.4  [123I]-MIBG -- 6.6.5  Other Radiolabelled Peptide Receptor Tracers.

6.7  Therapy of Neuroendocrine Neoplasms -- 6.7.1  Peptide Receptor-Based Radionuclide Therapy (PRRT/PRRNT) -- 6.7.2  [177Lu]-DOTA0-



Tyr3-Octreotate -- 6.7.3  Dosimetry -- 6.7.4  [90Y]-DOTA0-Tyr3-Octreotide -- 6.7.5  [90Y]-Microspheres and [166Ho]-Microspheres -- 6.7.6  [131I]-MIBG -- 6.8  Summary -- References -- 7: 123/131I-MIBG SPECT/CT for Tumour Imaging -- 7.1  Introduction -- 7.2  Physical Properties of 123I and 131I -- 7.3  Indications for mIBG Scan -- 7.4  Patient Preparation -- 7.5  Interfering Drugs -- 7.6  Contraindications -- 7.7  Dose Calculation -- 7.8  Image Acquisition -- 7.9  Acquisition of SPECT/CT -- 7.10  Reconstruction of SPECT/CT -- 7.11  Radiation Exposure -- 7.12  Physiological mIBG Uptake and Distribution -- 7.13  The Importance of mIBG SPECT and SPECT/CT -- 7.14  MIBG SPECT/CT in Neuroblastoma -- 7.14.1  Interpretation of the Findings: What Is Physiological? -- 7.14.2  Image Interpretation -- 7.14.2.1  False-Negative Findings -- 7.14.2.2  False-Positive Findings -- 7.14.3  SPECT/CT: Reducing False-Negative and -Positive Results -- 7.15  MIBG SPECT/CT in Pheochromocytoma and Paraganglioma -- 7.15.1  Interpretation of the Findings -- 7.16  mIBG SPECT/CT in Medullary Thyroid Carcinoma -- 7.16.1  Imaging Procedures -- References -- 8: Bone SPECT/CT in Oncology -- 8.1  Introduction -- 8.2  Radiopharmaceutical for Bone Scintigraphy/SPECT-CT -- 8.3  Radiopharmaceutical Activity -- 8.4  Bone SPECT/CT Patient Preparation -- 8.5  Image Acquisition Protocol -- 8.6  Role of SPECT-CT in Bone Metastases -- 8.7  Radiological Imaging -- 8.8  Bone Scintigraphy -- 8.9  Bone SPECT-CT -- 8.10  Artifacts on SPECT/CT -- 8.11  Literature Evidence on the Role of Bone SPECT/CT in Metastases -- 8.11.1  Primary Bone Malignancy -- References -- 9: Bone SPECT/CT in Orthopaedics -- 9.1  Introduction -- 9.1.1  Indications -- 9.1.2  Radiopharmaceuticals.

9.1.3  Radiopharmaceutical Activity -- 9.2  Bone SPECT/CT: Patient Preparation -- 9.3  Image Acquisition Protocol -- 9.4  Bone SPECT/CT in Different Benign Bone Conditions -- 9.4.1  Enchondroma -- 9.4.2  Shin Splint -- 9.4.2.1  SPECT-CT Findings -- 9.4.3  Avascular Necrosis -- 9.4.3.1  SPECT-CT Findings -- 9.4.4  Sacroiliitis -- 9.4.4.1  SPECT-CT Findings -- 9.4.5  Paget's Disease -- 9.4.5.1  SPECT-CT Findings -- 9.4.6  Fibrous Dysplasia -- 9.4.6.1  SPECT-CT Findings -- 9.4.7  Hypertrophic Pulmonary Osteoarthropathy -- 9.4.7.1  SPECT-CT Findings -- 9.4.8  Trauma -- 9.4.8.1  SPECT-CT Findings -- 9.4.9  Identification of Pain Generator (Prosthesis Related) -- 9.4.9.1  SPECT-CT Findings -- 9.4.10  Complex Regional Pain Syndrome -- 9.4.10.1 SPECT-CT Findings -- 9.4.11  Bone Infarct -- 9.4.11.1 SPECT-CT Findings -- 9.4.12  Heterotopic Ossification -- 9.4.12.1 SPECT-CT Findings -- 9.4.13  Condylar Hyperplasia -- 9.4.13.1 SPECT-CT Findings -- 9.4.14  Graft Viability Evaluation -- 9.4.14.1 SPECT-CT Findings -- 9.4.15  Vertebral Compression Fracture -- 9.4.15.1 SPECT-CT Findings -- 9.4.16  Spondylodiscitis -- 9.4.16.1 SPECT-CT Findings -- 9.4.17  Intraosseous Disc Herniation -- 9.4.17.1 SPECT-CT Findings -- 9.4.18  Osteomyelitis -- 9.4.18.1 SPECT-CT Findings -- References -- 10: SPECT/CT for Imaging of Coronary Artery Disease -- 10.1  Introduction -- 10.2  Myocardial Perfusion Imaging -- 10.3  Cardiac CT -- 10.3.1  Coronary Artery Calcium CT -- 10.3.2  Coronary Computed Tomographic Angiography -- 10.4  Integration of Nuclear MPI and CT -- 10.4.1  Integration of CT with MPI for Attenuation Correction -- 10.4.2  MPI and CAC -- 10.4.3  MPI and CCTA -- 10.5  Radiation Exposure -- 10.6  Clinical Applications -- 10.7  Future Perspective of Cardiac SPECT/CT -- References -- 11: SPECT/CT in Sentinel Node Scintigraphy -- 11.1  Introduction -- 11.2  Clinical Background.

11.3  Technical SPECT-CT Aspects for SN Imaging -- 11.4  Comprehensive Interpretation of Lymphoscintigraphy and SPECT/CT -- 11.5  Clinical Relevance of SPECT/ CT -- 11.5.1  Cutaneous Melanoma



-- 11.5.2  Breast Cancer -- 11.5.3  Head and Neck Malignancies -- 11.5.4  Pelvic and Retroperitoneal Malignancies -- 11.5.5  Other Malignancies -- 11.6  General Indications of SPECT/CT -- 11.7  SPECT/CT as a Roadmap for Intraoperative Detection of Sentinel Nodes -- 11.8  New Strategies Combining SPECT/CT and PET/CT -- References -- 12: Lung SPECT/CT -- 12.1  Introduction -- 12.2  Limitations of Planar Lung Scintigraphy -- 12.3  Advantages of SPECT Imaging -- 12.4  Need for Correlation with Anatomical Imaging -- 12.5  Combining Functional and Anatomical Images -- 12.5.1 Visual and Software Fusion -- 12.5.2 Hardware Fusion -- 12.6  V/Q Lung SPECT/CT -- 12.6.1 SPECT and CTPA Fusion -- 12.6.2 Combined V/Q SPECT with Low-Dose CT -- 12.6.2.1  Overview -- 12.6.2.2  Protocols -- Ventilation -- Perfusion -- SPECT: Gamma Camera Hardware, Image Acquisition and Processing -- CT Protocols for Use with SPECT V/Q Scans -- Image Display and Reviewing -- 12.7  Clinical Value of V/Q SPECT/ CT -- 12.8  Is the Ventilation Scan Necessary? -- 12.9  How Does V/Q SPECT/CT Compare with CTPA? -- 12.10  Clot Localisation -- 12.11  Consolidative Opacities -- 12.12  Barriers to Implementation of V/Q SPECT/CT -- 12.13  Thrombus Imaging -- 12.14  V/Q SPECT/CT: Role in Applications Other than PE -- 12.14.1 Radiotherapy Treatment Planning -- 12.14.2 Lung Reduction Surgery Planning -- 12.15  Further Uses -- 12.16  Quantitative V/Q SPECT -- 12.17  Conclusion -- References -- 13: Therapy Planning with SPECT/CT in Radioembolization of Liver Tumours -- 13.1  Introduction -- 13.2  The Significance of 99mTc-MAA SPECT/CT Liver Perfusion Imaging in the Treatment Planning of RE -- 13.3  Image Acquisition.

13.4  99mTc-MAA SPECT/CT in the Evaluation of Extrahepatic Deposition of Tracer.