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1. |
Record Nr. |
UNINA9910674022603321 |
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Titolo |
Glycosaminoglycans and Proteoglycans / / Barbara Mulloy, editor |
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Pubbl/distr/stampa |
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Basel, Switzerland : , : MDPI, , 2018 |
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Descrizione fisica |
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1 online resource (v, 215 pages) : illustrations |
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Disciplina |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Sommario/riassunto |
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Proteoglycans (PGs) are glycoconjugates in which a protein or peptide core is substituted with polysaccharide chains known as glycosaminoglycans (GAGs). The GAG sidechains carry a significant proportion of the functionality of PGs, interacting with many proteins to form structural units in the extracellular matrix and to modulate the transport and signalling of small proteins acting as morphogens, growth factors and cytokines. Purified GAGs such as heparin and hyaluronan are in common use as therapeutic agents, with many more PG-based natural products, synthetic and semi-synthetic mimetics on the way; in addition, potential therapeutic strategies involving PG/GAG biosynthesis and degradation as targets are currently in development. |
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2. |
Record Nr. |
UNICAMPANIAVAN00277897 |
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Titolo |
Mathematics of Public Health : Proceedings of the Seminar on the Mathematical Modelling of COVID-19 / V. Kumar Murty, Jianhong Wu editors |
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Descrizione fisica |
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Soggetti |
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00B25 - Proceedings of conferences of miscellaneous specific interest [MSC 2020] |
92-XX - Biology and other natural sciences [MSC 2020] |
92D30 - Epidemiology [MSC 2020] |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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